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Left ventricular wall motion abnormalities in 80 patients with systemic sclerosis

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Summary

Segmental analysis of left ventricular wall motion was performed in 80 patients with systemic sclerosis by echocardiography. Half of the cases showed normal wall motion. Eighteen of the 57 patients with limited cutaneous systemic sclerosis (31.6%) exhibited hypokinetic wall motion abnormalities, while five of the 23 cases with diffuse cutaneous systemic sclerosis (21.7%) had similar findings. The three cases showing akinesis also belonged to the limited scleroderma subgroup. Our findings show that hypokinetic wall motion abnormalities can be detected in a remarkably high proportion of cases with limited cutaneous systemic sclerosis.

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References

  1. Clements, P.J., Lachenbruch, P.A., Furst, D.E., Paulus, H.E., Sterz, M.G. Cardiac score. A semiquantitative measure of cardiac involvement that improves prediction of prognosis in systemic sclerosis. Arthritis Rheum 1991, 34, 1371–1380.

    PubMed  Google Scholar 

  2. D'Angelo, W.A., Fries, J.F., Masi, A.T., Shulman, L.E. Pathologic observations in systemic sclerosis (scleroderma). A study of fifty-eight autopsy cases and fifty-eight matched controls. Am J Med 1969, 46, 428–440.

    PubMed  Google Scholar 

  3. Hegedüs I., Czirják L. Left ventricular wall thickness and disease duration in systemic sclerosis Postgrad Med J 1993, 69, 291–295.

    PubMed  Google Scholar 

  4. Follansbee, W.P., Miller, T.R., Curtiss, E.I., et al. A controlled clinicopathologic study of myocardial fibrosis in systemic sclerosis (scleroderma). J Rheumatol 1990, 17, 656–662.

    PubMed  Google Scholar 

  5. Follansbee, W.P., Curtiss, E.I., Medsger, T.A.J., et al. Physiologic abnormalities of cardiac function in progressive systemic sclerosis with diffuse scleroderma. N Engl J Med 1984, 310, 142–148.

    PubMed  Google Scholar 

  6. Hegedüs, I., Czirják, L. Septum and posterior wall thickness and disease duration in systemic sclerosis. J Intern Med 1991, 229, 383–384.

    Google Scholar 

  7. Alpert, M.A., Pressly, T.A., Mukerji, V., et al. Acute and longterm effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease. Am J Cardiol 1991, 68, 1687–1691.

    PubMed  Google Scholar 

  8. Wynn, J., Fineberg, N., Matzer, L., et al. Prediction of survival in progressive systemic sclerosis by multivariate analysis of clinical features. Am Heart J 1985, 110, 123–127.

    PubMed  Google Scholar 

  9. Czirják, L., Nagy, Z., Szegedi, G. Survival analysis of 118 patients with systemic sclerosis. J Int Med 1993, 234, 335–337.

    Google Scholar 

  10. Heger, J.J., Weyman, A.E., Wann, L.S., Dillon, J.C., Feigenbaum, H. Cross-sectional echocardiography in acute myocardial infarction: detection and localisation of regional left ventricular asynergy. Circulation 1979, 60: 531–538.

    PubMed  Google Scholar 

  11. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 1980, 23, 581–590.

    Google Scholar 

  12. LeRoy, E.C., Black, C., Fleischmajer, R., et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988, 15, 202–205.

    PubMed  Google Scholar 

  13. Czirják, L., Nagy, Z., Szegedi, G. Systemic sclerosis in the elderly. Clin Rheumatol 1992, 11, 483–485.

    PubMed  Google Scholar 

  14. Czirják, L., Bokk, Å., Csontos, G., Lôrincz, G., Szegedi, G. Clinical findings in 61 patients with progressive systemic sclerosis. Acta Derm Venereol Stockh 1989, 69, 533–536.

    PubMed  Google Scholar 

  15. Bulkley, B.H., Klacsmann, P.G., Hutchins, G.M. Angina pectoris, myocardial infarction and sudden cardiac death with normal coronary arteries: a clinicopathologic study of 9 patients with progressive systemic sclerosis. Am Heart J 1978, 95, 563–569.

    PubMed  Google Scholar 

  16. Anvari, A., Graninger, W., Schneider, B., Sochor, H., Weber, H., Schmidinger, H. Cardiac involvement in systemic sclerosis. Arthritis Rheum 1992, 35, 1356–1361.

    PubMed  Google Scholar 

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Hegedüs, I., Czirják, L. Left ventricular wall motion abnormalities in 80 patients with systemic sclerosis. Clin Rheumatol 14, 161–164 (1995). https://doi.org/10.1007/BF02214936

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  • DOI: https://doi.org/10.1007/BF02214936

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