Abstract
Myxoid tissue forms part of many benign and malignant soft-tissue tumors. The advent of percutaneous needle biopsy has made it important to be aware of the diagnostic implications of biopsy samples containing myxoid tissue. To determine whether the magnetic resonance imaging (MRI) characteristics could help establish the diagnosis, we compared the MR images of 11 tumors containing myxoid tissue with the resected tumor tissue.
In our small series of these rare tumors, the MRI characteristics allowed differentiation of intramuscular myxomas from malignant neoplasms containing myxoid tissue. Intramuscular myxomas meet the following conditions: (a) they are well circumscribed; (b) they arise within muscle; (c) T1-weighted images demonstrate uniform, decreased signal intensity; (d) T2-weighted images demonstrate uniform increased signal intensity; (e) contrast-enhanced images exhibit an inhomogeneous increase in signal intensity. If any of these conditions is not met, then a malignancy containing myxoid tissue should be suspected.
Similar content being viewed by others
References
Aisen AM, Martel W, Braunstein EM, et al. (1986) MRI and CT evaluation of primary bone and soft-tissue tumors. AJR 146:749
Ekelund L, Herrlin K, Rydholm A (1982) Computed tomography of intramuscular myxoma. Skeletal Radiol 9:14
Enzinger FM (1965) Intramuscular myxoma: a review and follow-up study of 34 cases. Am J Clin Pathol 43:104
Enzinger FM, Weiss SW (1988) Soft tissue tumors, 2nd edn. CV Mosby, St. Louis
Glass-Royal MC, Nelson MC, Albert F, et al. (1989) Case report 557: intramuscular myxoma in a patient with polyostotic fibrous dysplasia. Skeletal Radiol 18:392
Hashimoto H, Tsuneyoshi M, Daimara Y, Enjoji M, et al. (1986) Intramuscular myxoma: a clinicopathologic, immunohistochemical, and electron microscopic study. Cancer 58:740
Ireland DCR, Soule EH, Ivins JC (1973) Myxoma of somatic soft tissues: a report of 58 patients, 3 with multiple tumors. Mayo Clinic Proc 48:401
Kalmar JA, Miller KD, Eick JJ, et al. (1988) A review of applications of MRI in soft tissue and bone tumors. Orthopedics 11:417
Kilcoyne RF, Richardson ML, Porter BA, et al. (1988) Magnetic resonance imaging of soft tissue masses. Clin Orthop 228:13
Kransdorf MJ, Jelinek JS, Moser RP, et al. (1989) Soft tissue masses: diagnosis using MR imaging. AJR 153:541
Kransdorf MJ, Moser RP, Jelinek SJ, et al. (1989) Intramuscular myxoma: MR features. J Comput Assist Tomogr 13:836
London J, Kim EE, Wallace S, Shirkhoda A, Coan J, Evans H (1989) MR imaging of liposarcomas: correlation with MR features and histology. J Comput Assist Tomogr 13:832
Mackenzie DH (1981) The myxoid tumors of somatic soft tissues. Am J Surg Pathol 5:443
McCook TA, Martinez S, Korobkin M, et al. (1981) Intramuscular myxoma: radiographic and computed tomographic findings and pathologic correlation. Skeletal Radiol 7:15
Milgram JW, Preininger RE (1973) Calcifying myxoma: a case report. J Bone Joint Surg [Am] 55:401
Negendank WG, Crowley MG, Ryan JR, et al. (1989) Bone and soft tissue lesions: diagnosis with combined H-1 MR imaging and P-31 MR spectroscopy. Radiology 173:181
Petasnick JP, Turner DA, Charters JR, et al. (1986) Soft-tissue masses of the locomotor system: comparison of MR imaging with CT. Radiology 160:125
Pettersson H, Hudson TM, Springfield S, Kaude JV (1985) Cystic intramuscular myxoma: report of a case. Acta Radiol [Diagn] (Stockh) 26:425
Pettersson H, Slone RM, Spanier S, et al. (1988) Musculoskeletal tumors: T1 and T2 relaxation times. Radiology 167:783
Stout AP (1948) Myxoma, the tumor of primitive mesenchyme. Ann Surg 127:706
Sundaram M, McGuire MH, Herbold DR (1988) Magnetic resonance imaging of soft tissue masses: an evaluation of 53 histologically proven tumors. Magnetic Resonance Imaging 6:237
Sundaram M, McDonald DJ, Merenda G (1989) Intramuscular myxoma: a rare but important association with fibrous dysplasia. AJR 153:107
Sundaram M, Baran G, Merenda G, McDonald DJ (1990) Myxoid liposarcoma: magnetic resonance imaging appearances with clinical and histologic correlation. Skeletal Radiol 19:359
Totty WG, Murphy WA, Lee JKT (1986) Soft-tissue tumors: MR imaging. Radiology 160:135
Weekes RG, Berquist TH, McLeod RA, Zimmer WD (1985) Magnetic resonance imaging in soft tissue tumors: comparison with computed tomography. Magnetic Resonance Imaging 3:345
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Peterson, K.K., Renfrew, D.L., Feddersen, R.M. et al. Magnetic resonance imaging of myxoid containing tumors. Skeletal Radiol. 20, 245–250 (1991). https://doi.org/10.1007/BF02341657
Issue Date:
DOI: https://doi.org/10.1007/BF02341657