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Computer control of respiration and anaesthesia

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Abstract

Control of a number of interactive physiological variables by an online computer, operating in real time, is demonstrated. It is shown that a computer-controlled system, by monitoring values of arterial blood pressure, end-tidal CO2 percentage and inspired O2 percentage, can maintain the respiration and anaesthesia of a ventialted animal within close tolerances. Under computer control, it is possible to compensate for random disturbances of the system parameters, and changes in the desired levels of the variables can be dealt with automatically.

Sommaire

Cet article décrit le contrôle d'un certain nombre de variables physiologiques interactives par un ordinateur on-line fonctionnant en temps réel. Il est démontré qu'un système contrôlé par ordinateur peut, en surveillant les valeurs de la pression artérielle, le pourcentage de CO2 en fin de cycle et le pourcentage de O2 respiré, maintenir la respiration et l'anesthésie d'un animal recevant de l'air dans des tolérances strictes. Sous le contrôle d'un ordinateur, il est possible de compenser les perturbations aléatoires des paramètres du système et l'on peut traiter automatiquement les changements affectant les niveaux désirés des variables.

Zusammenfassung

Die Steuerung einer Anzhhl von in Wechselwirkung stehenden physiologischen Variablen durch einen on-line, in real-time arbeitenden Rechner wird vorgeführt. Es wird gezeigt, dass ein komputergesteuertes System durch die Überwachung des arteriellen Blutdruckes, der endzyklischen CO2 Konzentration und der inspirierten O2 Konzentration, die Respiration und d Anaesthesie eines beatmeten Tieres innerhalb enger Toleranzgrenzen erbalten kann. Es ist möglich, unter Rechnerkontrolle statistisch auftretende Störungen der Systemparameter anzukompensieren, und Abweichungen von den gewünschten Werten der Variablen können automatisch berücksichtigt werden.

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References

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Coles, J.R., Brown, W.A. & Lampard, D.G. Computer control of respiration and anaesthesia. Med. & biol. Engng. 11, 262–267 (1973). https://doi.org/10.1007/BF02475535

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  • DOI: https://doi.org/10.1007/BF02475535

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