Abstract
A 52-year-old man was admitted to our clinic with severe headache and bilateral papilledema. Magnetic resonance (MR) images on admission demonstrated diffuse swelling of the cerebral cortex without formation of a tumor mass. Biopsy revealed diffuse infiltration with neoplastic glial cells. After radiation and chemotherapy, the MR images returned to normal. The morphological and neurological features of the present case met the criteria for gliomatosis cerebri. However, this patient showed an unusually good response to radiation and chemotherapy.
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Artigas J, Cervos-Navarro J, Iglesias JR, et al. (1985) Gliomatosis cerebri: clinical and histological findings. Clin Neuropathol 4:135–148
Burger PC, Scheithauer BW (1993) Gliomatosis cerebri. In: Burger PC, Scheithauer BW (eds) Tumors of the central nervous system. Atlas of tumor pathology, third series, fascicle 10. Armed Forces Institute of Pathology, Washington, DC, pp 72–73
Cervos-Navarro J, Artigas J, Aruffo C, et al. (1987) The fine structure of gliomatosis cerebri. Virchows Arch A 411:93–98
Felsberg GJ, Silver SA, Brown MT, et al. (1994) Radiologic-pathologic correlation gliomatosis cerebri. AJNR 15:1745–1753
Kleihues P, Burger PC, Scheithauer BW (1993) Gliomatosis cerebri. In: Kleihues P, Burger PC, Scheithauer BW (eds) Histological typing of tumors of the central nervous system. 2nd ed. Springer-Verlag, Berlin, pp 21–22
Dickson DW, Horoupian DS, Thal LJ, et al. (1988) Gliomatosis cerebri presenting with hydrocephalus and dementia. AJNR 9:200–202
Giovagnoli AR, Strada L, Pollo B, et al. (1992) Gliomatosis cerebri. Report of a case with isolated amnestic disorders. Ital J Neurol Sci 13:503–506
Kandled RH, Smith CM, Broome JC, et al. (1991) Br J Neurol 5:187–193
Scheinker IM, Evans JP (1943) Diffuse cerebral glioblastosis. J Neuro-pathol Exp Neurol 2:78–189
Nevin S (1938) Gliomatosis cerebri. Brain 61:170–191
Shin YM, Chang KH, Han MH, et al. (1993) Gliomatosis cerebri: comparison of MR and CT features AJR 161:859–862
Ueki K, Matsutani M, Nakamurta O, et al. (1990) Clinical diagnosis of gliomatosis cerebri by radioimages (in Japanese). Neurol Surg 18:89–93
Yanaka K, Kamezaki T, Kobayashi E, et al. (1992) MR imaging of diffuse glioma. AJNR 13:349–351
Romero FJ, Ortega A, Titus F, et al. (1988) Gliomatosis cerebri with formation of a glioblastoma multiform—study and follow-up by magnetic resonance and computed tomography J Comput Assist Tomogr 12:253–257
Galatioto S, Marafioti T, Cavallari V, et al. (1993) Gliomatosis cerebri. Clinical, neuropathological, immunohistochemical and morphometric studies. Zbl Pathol 139:261–267
Koslow SA, Classen D, Hirsch WL et al. (1993) Gliomatosis cerebri: a case report with autopsy correlation. Neuroradiology 34:331–333
Rippe DJ, Boyko OB, Fuller GN, et al. (1990) Gadopentetate-dimeglumine-enhanced MR imaging of gliomatosis cerebri: appearance mimicking leptomeningeal tumor dissemination. AJNR 11:800–801
Ross IB, Robitaille Y, Villemure J, et al. (1991) Diagnosis and management of gliomatosis cerebri: recent trends. Surg Neurol 36:431–440
Hara A, Sakai N, Yamada H, et al. (1991) Assessment of proliferative potential in gliomatosis cerebri. J Neurol 238:80–82
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Kannuki, S., Hondo, H., Ii, K. et al. Gliomatosis cerebri with good prognosis. Brain Tumor Pathol 14, 53–57 (1997). https://doi.org/10.1007/BF02478869
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DOI: https://doi.org/10.1007/BF02478869