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Metaphyseal impaction fractures in acute lymphoblastic leukemia

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Summary

Patients with acute lymphatic leukaemia frequently are osteoporotic. A small subset of these develop disabling metaphyseal transverse fractures, usually bilateral and in the lower limb. These impaction fractures have a characteristic appearance and develop in recently laid down bone. They may develop ab initio or during therapy. Magnesium deficiency is found in these patients.

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Manson, D., Martin, R.F. & Cockshott, W.P. Metaphyseal impaction fractures in acute lymphoblastic leukemia. Skeletal Radiol. 17, 561–564 (1989). https://doi.org/10.1007/BF02569401

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