Abstract
High vaginal swabs (HVS) of 1792 expectant mothers were sent for culture at the time of delivery, prior to first vaginal examination. The newborns were followed-up for development of superficial or deep infections. Appropriate cultures of the babies who developed infections were sent. Bacterial growth of predominantly gram-ve organisms was obtained in 1026 (57%) HVS. Infection developed in 48 (27%) babies in 1 st 72 hours of life, of which 28 had deep infection while the rest had superficial infection. Vertical transmission of organisms was documented in 24 (1.3%) mother—baby dyads and the same was 72% in newborns who were at risk of developing sepsis by septicemia scoring, showing a significantly higher incidence of vertical transmission and subsequent sepsis in high risk newborns.
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Beargie R, Lynd P, Tucker E, Duhring J. Perinatal infection and vaginal flora.Am J Obstet Gynecol 1975; 122: 31–33.
Hosmer ME. Screening method for identification of infected infants.Pediatrics 1972; 49: 283–286.
Tucker VP, Bhakoo ON. Scoring system for prediction of early neonatal infection.Indian Pediatr 1974; 11: 597–601.
Kishore K, Deorari AR, Singh M, Bhujwala RA. Early onset neonatal sepsis, vertical transmission from maternal genital tract.Indian Pediatr 1987; 24: 45–48.
Bhatia BD, Chugh SP, Narang P. Bacterial flora of pregnant women at admission in maternity wards.Indian Pediatr 1986; 23: 17–20.
Ross J. Perinatal implication of lower genital tract flora.Perinatal Infection. CIBA symposium 1980; 69: 77–80.
Udani RH, Vaze S, Roys M, Paul SS. Premature rupture of amniotic membranes and neonatal infection—Pridecetive value of bacteriologic culture from different sites.Indian J Pediatr 1980; 47: 137–140.
Galark RP, Larson B, Ohm MJ. Vaginal flora and its role in disease entities.Clin Obstet Gynecol 1976; 19: 61–81.
Klein JO, Remington JS. Infections acquired by the newborn infant during birth. In: Remington JS, Klein JO. eds.Current concepts of infections of the fetus and newborn infant, in infectious disease of fetus and newborn infant. Third edition London: Saunders, 1991: pp 11–12.
Karpuch J, Goldberg M, Kohcleol D. Neonatal bacterimia—A 4-years prospective study.Isr J Med Sci 1983; 19: 963–966.
Bada HS, Alojipan LC, Andrews BF. Premature rupture of membranes and its effect on the newborn.Pediatr Clin North Am 1977; 24: 491–500.
Chaturvedi P, Agrawal M, Narang P. Analysis of blood culture isolate from a rural hospital.Indian Pediatr 1989; 26: 460–465.
Sharma PP, Haldar D, Dutta AK et al. Bacteriological profile of neonatal septicemia.Indian Pediatr 1987; 24: 1011–1017.
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Ayengar, V., Madhulika & Vani, S.N. Neonatal sepsis due to vertical transmission from maternal genital tract. Indian J Pediatr 58, 661–664 (1991). https://doi.org/10.1007/BF02820186
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DOI: https://doi.org/10.1007/BF02820186