Summary
The general profile of pain in the evolution of pancreatitis was analysed in relation to exocrine and endo:rine pancreatic function in 127 patients with primary chronic pancreatitis followed up over 3 years.
Pain decreased or disappeared in 67.8% and 55.9% of calcifying and non-calcifying pancreatitis, respectively. While pancreatic exocrine function remained abnormal in spite of an improvement of pain in 72% of 18 patients with calcifying pancreatitis, it improved with the amelioration of pain in 64.0% of 25 patients with non-calcifying pancreatitis during the follow-up period. Alcohol abstinence seems most important for pain relief in patients with non-calcifying pancreatitis but not calcifying pancreatitis. Changes in glucose tolerance test were not related with those in pain. In calcifying pancreatitis, 69.2% of patients with calcifying pancreatitis were diabetic or became so, while 66.7% of patients with non-calcifying pancreatitis remained non-diabetic during the observation period.
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Kondo, T., Hayakawa, T., Noda, A. et al. Follow-up study of chronic pancreatitis. Gastroenterol Jpn 16, 46–53 (1981). https://doi.org/10.1007/BF02820424
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DOI: https://doi.org/10.1007/BF02820424