Zusammenfassung
Bei 12 Patienten mit Glaucoma chronicum simplex und unterschiedlich großen Gesichtsfelddefekten wurden skotopische Helligkeits-Elektroretinogramme (H-ERG) abgeleitet. Nur Patienten, welche nach fistulierender Augenoperation keine medikamentöse Therapie benötigten, wurden in die Studie eingeschlossen.
Patienten mit geringeren Gesichtsfelddefekten hatten normale b-Wellen und nur gering verkleinerte oszillatorische Potentiale (OPs). B-Wellen und OPs von Patienten mit größeren Gesichtsfelddefekten wiesen im Vergleich zu einer altersentsprechenden Kontrollgruppe signifikant erniedrigte Amplituden auf.
Unsere Ergebnisse sprechen für einen über die Ganglienzellschicht hinausgehenden Netzhautschaden bei Glaukom.
Summary
In 12 patients suffering from primary open angle glaucoma and different sizes of visual field defects scotopic luminance-ERGs were recorded. Only patients that underwent fistulating glaucoma surgery and did not need additional drug therapy were included in the study.
Patients with minor visual field defects had normal bwaves and only slightly decreased oscillatory potentials (OPs). B-waves and OPs of patients with severe visual field defects showed significant lower amplitudes compared to an age matched control group.
Our results indicate that retinal damage exceeds the ganglion cell layer in patients with glaucoma.
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Vass, C., Menapace, R. & Gottlob, I. Veränderungen des Helligkeits-Elektroretinogramms bei Patienten mit Glaucoma chronicum simplex. Spektrum Augeheilkd 4, 226–229 (1990). https://doi.org/10.1007/BF03163617
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DOI: https://doi.org/10.1007/BF03163617