Abstract.
We report the case of a 3-year-old girl who presented with near-lethal pulmonary thrombembolism 3 weeks after an uneventful Fontan operation. Complete occlusion of the left lower lobe pulmonary artery had occurred together with a cerebral infarction. Recombinant tissue plasminogen activator (rt-Pa) was used for thrombolysis because of its short half-life and its clot-selective properties. To further minimize the systemic effects of rt-PA, local catheter-directed lysis was performed. A prolonged course of low-dose rt-PA therapy achieved complete lysis without side effects.
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Beitzke, A., Zobel, G., Zenz, W. et al. Catheter-Directed Thrombolysis with Recombinant Tissue Plasminogen Activator for Acute Pulmonary Embolism After Fontan Operation. Pediatr Cardiol 17, 410–412 (1996). https://doi.org/10.1007/s002469900091
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DOI: https://doi.org/10.1007/s002469900091