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Effect of computer-aided detection as a second reader in multidetector-row CT colonography

  • Gastrointestinal
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Abstract

Our purpose was to assess the effect of computer-aided detection (CAD) on lesion detection as a second reader in computed tomographic colonography, and to compare the influence of CAD on the performance of readers with different levels of expertise. Fifty-two CT colonography patient data-sets (37 patients: 55 endoscopically confirmed polyps ≥0.5 cm, seven cancers; 15 patients: no abnormalities) were retrospectively reviewed by four radiologists (two expert, two nonexpert). After primary data evaluation, a second reading augmented with findings of CAD (polyp-enhanced view, Siemens) was performed. Sensitivities and reading time were calculated for each reader without CAD and supported by CAD findings. The sensitivity of expert readers was 91% each, and of nonexpert readers, 76% and 75%, respectively, for polyp detection. CAD increased the sensitivity of expert readers to 96% (P = 0.25) and 93% (P = 1), and that of nonexpert readers to 91% (P = 0.008) and 95% (P = 0.001), respectively. All four readers diagnosed 100% of cancers, but CAD alone only 43%. CAD increased reading time by 2.1 min (mean). CAD as a second reader significantly improves sensitivity for polyp detection in a high disease prevalence population for nonexpert readers. CAD causes a modest increase in reading time. CAD is of limited value in the detection of cancer.

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Authors and Affiliations

  1. Department of Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria

    Thomas Mang, Philipp Peloschek, Christina Plank, Andrea Maier, Michael Weber, Christian Herold & Wolfgang Schima

  2. Department of Clinical Radiology-Grosshadern Campus, University of Munich, Marchioninistrasse 15, 81377, Munich, Germany

    Anno Graser

  3. Computer-Aided Diagnosis and Therapy, Siemens Medical Solutions, Malvern, Philadelphia, 19355, USA

    Luca Bogoni

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  1. Thomas Mang
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Correspondence to Thomas Mang.

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Mang, T., Peloschek, P., Plank, C. et al. Effect of computer-aided detection as a second reader in multidetector-row CT colonography. Eur Radiol 17, 2598–2607 (2007). https://doi.org/10.1007/s00330-007-0608-z

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  • DOI: https://doi.org/10.1007/s00330-007-0608-z

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