Abstract
Objectives
To evaluate patellofemoral congruency measurements on MRI and correlate the findings with severity of ipsilateral osteoarthritis.
Methods
We retrospectively reviewed 650 consecutive knee MRI examinations from 622 patients divided into two age groups: ≤50 and >50 year-old. The femoral sulcus angle (SA) and depth (SD), lateral patellar displacement (LPD), lateral patellofemoral angle (LPFA), tibial tubercle-trochlear groove (TT-TG) distance and Insall-Salvati index as well as the grade of focal cartilage defects (ranging from I to IV) in the patellofemoral region were assessed in each subject on axial and sagittal fat-saturated intermediate-w MR images.
Results
A significant difference exists between normal and knees with patellofemoral joint osteoarthritis regarding SA (p = 0.0002 and <0.0001), SD (p = 0.0004 and <0.0001), LPD (p = 0.0014 and 0.0009) and LPFA (p = 0.0002 and 0.0003) in both age groups (≤50 and >50 respectively). Significant correlation was found between grading of cartilage defects and SA (rho = 0.21, p = 0.0001 and 0.443, <0.0001), SD (rho = −0.198, p = 0.0003 and −0.418, <0.0001), LPD (rho = 0.176, p = 0.0013 and 0.251, 0.0002) and LPFA (rho = −0.204, p = 0.0002 and −0.239, 0.0005) in both age groups.
Conclusions
Knee joint anterior malalignment is multivariably associated with patellofemoral osteoarthritis.
Key Points
• MRI is an excellent method to evaluate knee alignment and articular cartilage damage.
• Significant associations exist between alignment parameters and osteoarthritis of the patellofemoral joint.
• The “sulcus angle” and “sulcus depth” were the most valuable osteoarthritic markers.
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References
Woolf AD, Pfleger B (2003) Burden of major musculoskeletal conditions. Bull World Health Organ 81:646–656
Felson DT, McAlindon TE, Anderson JJ, Naimark A, Weissman BW, Aliabadi P, Evans S, Levy D, LaValley MP (1997) Defining radiographic osteoarthritis for the whole knee. Osteoarthr Cartil 5:241–250
Guermazi A, Zaim S, Taouli B, Miaux Y, Peterfy CG, Genant HG (2003) MR findings in knee osteoarthritis. Eur Radiol 13:1370–1386
Arendt E (2005) Anatomy and malalignment of the patellofemoral joint: its relation to patellofemoral arthrosis. Clin Orthop 436:71–75
Duncan R, Hay E, Saklatvala J, Croft P (2006) Prevalence of radiographic osteoarthritis: it all depends on your point of view. Rheumatology 45:757–760
Davies AP, Vince AS, Shepstone L, Donell ST, Glasgow MM (2002) The radiologic prevalence of patellofemoral osteoarthritis. Clin Orthop 402:206–212
Hinman RS, Crossley KM (2007) Patellofemoral osteoarthritis: an important subgroup of knee osteoarthritis. Rheumatology 46:1057–1062
Grelsamer RP, Dejour D, Gould J (2008) The pathophysiology of patellofemoral arthritis. Orthop Clin North Am 39:269–274
Mäenpää H, Lehto MU (1997) Patellofemoral osteoarthritis after patellar dislocation. Clin Orthop 339:156–162
Kalichman L, Zhang Y, Niu J, Goggins J, Gale D, Felson D, Hunter DJ (2007) The association between patellar alignment and patellofemoral joint osteoarthritis features—an MRI study. Rheumatology 46:1303–1308
Yang B, Tan H, Yang L, Dai G, Guo B (2009) Correlating anatomy and congruence of the patellofemoral joint with cartilage lesions. Orthopedics 32:20
Ali SA, Helmer R, Terk MR (2010) Analysis of the patellofemoral region on MRI: association of abnormal trochlear morphology with severe cartilage defects. AJR Am J Roentgenol 194:721–727
Wittstein JR, Bartlett EC, Easterbrook J, Byrd JC (2006) Magnetic resonance imaging evaluation of patellofemoral malalignment. Arthroscopy 22:643–649
Sanders TG, Loredo R, Grayson D (2001) Computed tomography and magnetic resonance imaging evaluation of patellofemoral instability. Oper Tech Sports Med 9:152–163
Beaconsfield T, Pintore E, Maffulli N, Petri GJ (1994) Radiologic measurements in patellofemoral disorders. A review. Clin Orthop 308:18–28
Walker C, Cassar-Pullicino VN, Vaisha R, McCall IW (1993) The patello-femoral joint—a critical appraisal of its geometric assessment utilizing conventional axial radiography and computed arthro-tomography. Br J Radiol 66:755–761
Koëter S, Horstmann WG, Wagenaar FC, Huysse W, Wymenga AB, Anderson PG (2007) A new CT scan method for measuring the tibial tubercle trochlear groove distance in patellar instability. Knee 14:128–132
Brittberg M, Winalski CS (2003) Evaluation of cartilage injuries and repair. J Bone Joint Surg Am 85:58–69
DeLong ER, DeLong DM, Clarke-Pearson DL (1988) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44:837–845
Insall J, Falvo KA, Wise DW (1976) Chondromalacia patellae: a prospective study. J Bone Joint Surg Am 58:1–8
Outerbridge RE (1964) Further studies on the etiology of chondromalacia patellae. J Bone Joint Surg Br 46:179–190
Endo Y, Schweitzer ME, Bordalo-Rodrigues M, Rokito AS, Babb JS (2007) MRI quantitative morphologic analysis of patellofemoral region: lack of correlation with chondromalacia patellae at surgery. AJR Am J Roentgenol 189:1165–1168
Goodfellow J, Hungerford DS, Zindel M (1976) Patellofemoral joint mechanics and pathology: functional anatomy of the patello-femoral joint. J Bone Joint Surg Br 58:287–290
McNally EG (2001) Imaging assessment of anterior knee pain and patellar maltracking. Skelet Radiol 30:484–495
Pfirrmann CW, Zanetti M, Romero J, Hodler J (2000) Femoral trochlear dysplasia: MR findings. Radiology 216:858–864
Carrillon Y, Abidi H, Dejour D, Fantino O, Moyen B, Tran-Minh VA (2000) Patellar instability: assessment on MR images by measuring the lateral trochlear inclination-initial experience. Radiology 216:582–585
Davies AP, Costa ML, Shepstone L, Glasgow MM, Donell S (2000) The sulcus angle and malalignment of the extensor mechanism of the knee. J Bone Joint Surg Br 82:1162–1166
Link TM (2010) MR imaging in osteoarthritis: hardware, coils, and sequences. Magn Reson Imaging Clin N Am 18:95–110
Post WR, Fulkerson JP (1992) Distal realignment of the patellofemoral joint. Indications, effects, results, and recommendations. Orthop Clin North Am 23:631–643
Lee TQ, Morris G, Csintalan RP (2003) The influence of tibial and femoral rotation on patellofemoral contact area and pressure. J Orthop Sports Phys Ther 33:686–693
Dejour H, Walch G, Nove-Josserand L, Guier C (1994) Factors of patellar instability: an anatomic radiographic study. Knee Surg Sports Traumatol Arthrosc 2:19–26
Grelsamer RP (2000) Current concepts review—patellar malalignment. J Bone Joint Surg Am 82A:1639–1650
Donell S (2006) Patellofemoral dysfunction-extensor mechanism malalignment. Curr Orthopaed 20:103–111
Wagenaar FC, Koëter S, Anderson PG, Wymenga AB (2007) Conventional radiography cannot replace CT scanning in detecting tibial tubercle lateralisation. Knee 14:51–54
Diks MJ, Wymenga AB, Anderson PG (2003) Patients with lateral tracking patella have better pain relief following CT-guided tuberosity transfer than patients with unstable patella. Knee Surg Sports Traumatol Arthrosc 11:384–388
Koëter S, Diks MJ, Anderson PG, Wymenga AB (2007) A modified tibial tubercle osteotomy for patellar maltracking: results at two years. J Bone Joint Surg Br 89:180–185
Insall J, Salvati E (1971) Patella position in the normal knee. Radiology 101:101–104
Al-Sayyad MJ, Cameron JC (2002) Functional outcome after tibial tubercle transfer for the painful patella alta. Clin Orthop 396:152–162
Bentley G, Dowd G (1984) Current concepts of etiology and treatment of chondromalacia patellae. Clin Orthop 189:209–228
Geenen E, Molenaers G, Martens M (1989) Patella alta in patellofemoral instability. Acta Orthop Belg 55:387–393
Simmons E Jr, Cameron JC (1992) Patella alta and recurrent dislocation of the patella. Clin Orthop 274:265–269
Singerman R, Davy DT, Goldberg VM (1994) Effects of patella alta and patella infera on patellofemoral contact forces. J Biomech 27:1059–1065
Chrisman OD (1986) The role of articular cartilage in patellofemoral pain. Orthop Clin North Am 17:231–234
Stefanik JJ, Zhu Y, Zumwalt AC, Gross KD, Clancy M, Lynch JA, Frey Law LA, Lewis CE, Roemer FW, Powers CM, Guermazi A, Felson DT (2010) Association between patella alta and the prevalence and worsening of structural features of patellofemoral joint osteoarthritis: the multicenter osteoarthritis study. Arthritis Care Res 62:1258–1265
Hart DJ, Spector TD (1993) The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. J Rheumatol 20:331–335
Felson DT, Zhang Y, Anthony JM, Naimark A, Anderson JJ (1992) Weight loss reduces the risk for symptomatic knee osteoarthritis in women. The Framingham Study. Ann Intern Med 116:535–539
Sandmark H, Hogstedt C, Lewold S, Vingard E (1999) Osteoarthrosis of the knee in men and women in association with overweight, smoking, and hormone therapy. Ann Rheum Dis 58:151–155
Cicuttini FM, Spector T, Baker J (1997) Risk factors for osteoarthritis in the tibiofemoral and patellofemoral joints of the knee. J Rheumatol 24:1164–1167
Roubenoff R (1996) Applications of bioelectrical impedance analysis for body composition to epidemiologic studies. Am J Clin Nutr 64:459S–462S
Teichtahl AJ, Wang Y, Wluka AE, Szramka M, English DR, Giles GG, O’Sullivan R, Cicuttini FM (2008) The longitudinal relationship between body composition and patella cartilage in healthy adults. Obesity (Silver Spring) 16:421–427
Smith TO, Davies L, Toms AP, Hing CB, Donell ST (2011) The reliability and validity of radiological assessment for patellar instability. A systematic review and meta-analysis. Skelet Radiol 40:399–414
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Tsavalas, N., Katonis, P. & Karantanas, A.H. Knee joint anterior malalignment and patellofemoral osteoarthritis: an MRI study. Eur Radiol 22, 418–428 (2012). https://doi.org/10.1007/s00330-011-2275-3
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DOI: https://doi.org/10.1007/s00330-011-2275-3