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Genetic variation in human gene expression

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Abstract

Gene expression variation has been the focus of many studies in the past few years. The relevance of gene regulation and gene expression to disease and the development of the technologies used to screen large numbers of genes simultaneously have allowed this rapid development. In this review we discuss issues relating to the biological information one obtains from such studies and the biological significance and use of signals from mapping of gene expression variation.

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Authors and Affiliations

  1. Division of Informatics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK

    Emmanouil T. Dermitzakis & Barbara E. Stranger

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  1. Emmanouil T. Dermitzakis
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  2. Barbara E. Stranger
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Correspondence to Emmanouil T. Dermitzakis.

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Dermitzakis, E.T., Stranger, B.E. Genetic variation in human gene expression. Mamm Genome 17, 503–508 (2006). https://doi.org/10.1007/s00335-006-0005-y

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  • DOI: https://doi.org/10.1007/s00335-006-0005-y

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