Abstract
We describe a case of remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome) in a 66-year-old man. This report discusses magnetic resonance imaging findings of RS3PE syndrome and the changes after steroid therapy.
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References
McCarty DJ, O’Duffy JD, Pearson L, Hunter JB (1985) Remitting seronegative symmetrical synovitis with pitting edema. JAMA 254:2763–2767
Schaeverbeke T, Fatout E, Marce S, Vernhes JP, Halle O, Antoine JF et al (1995) Remitting seronegative synovitis with pitting oedema: disease or syndrome? Ann Rheum Dis 54:681–684
Dudler J, Gerster JC, So A (1999) Polyarthritis and pitting oedema. Ann Rheum Dis 58:142–147
Queiro R (2004) RS3PE syndrome: a clinical and immunogenetical study. Rheumatol Int 24:103–105
Corvetta A, Giovagnoni A, Baldelli S, Ercolani P, Pomponio G, Luchetti MM et al (1992) MR imaging of rheumatoid hand lesions: comparison with conventional radiology in 31 patients. Clin Exp Rheumatol 10:217–222
Oide T, Ohara S, Oguchi K, Maruyama M, Yazawa M, Inoue K et al (2004) Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome in Nagano, Japan: clinical, radiological, and cytokine studies of 13 patients. Clin Exp Rheumatol 22:91–98
Cantini F, Salvarani C, Olivieri I, Barozzi L, Macchioni L, Niccoli L et al (1999) Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome: a prospective follow up and magnetic resonance imaging study. Ann Rheum Dis 58:230–236
Weyand CM, Hunder NN, Hicok KC, Hunder GG, Goronzy JJ (1994) HLA-DRB1 alleles in polymyalgia rheumatica, giant cell arteritis, and rheumatoid arthritis. Arthritis Rheum 37:514–520
Toussirot E, Bertier S, Wendling D, Tiberghien P (1998) Lack of association between HLA DRB1 alleles and RS3PE syndrome. Ann Rheum Dis 57:442
Vinci M, Malaguarnera L, Pistone G (2001) RS3PE and ovarian cancer. Ann Rheum Dis 60:429–432
Paira S, Graf C, Roverano S, Rossini J (2002) Remitting seronegative symmetrical synovitis with pitting oedema: a study of 12 cases. Clin Rheumatol 21:146–149
Cimmino MA, Silvestri E, Garlaschi G (2001) Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) as recurrence of aborted PMR. Ann Rheum Dis 60:303
Olivieri I, Salvarani C, Cantini F (1997) Remitting distal extremity swelling with pitting edema: a distinct syndrome or a clinical feature of different inflammatory rheumatic diseases? J Rheumatol 24:249–252
Takeguchi T, Sugawara Y, Kikuchi K, Miki H, Mochizuki T, Ikezoe J et al (2003) Remitting seronegative symmetric synovitis with pitting edema: scintigraphic and magnetic resonance imaging findings. Clin Nucl Med 28:766–768
Matsuda M, Sakura K, Fushimi T, Yamamoto K, Rokuhara S, Hosaka N et al (2004) Sarcoidosis with high serum levels of vascular endothelial factor (VEGF) showing RS3PE-like symptoms in extremities. Clin Rheumatol 23:252–255
Cantini F, Salvarani C, Olivieri I (1999) Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema. Clin Exp Rheumatol 17:741–744
Backhaus M, Kamradt T, Sandrock D, Loreck D, Fritz J, Wolf KJ et al (1999) Arthritis of the finger joints: a comprehensive approach comparing conventional radiography, scintigraphy, ultrasound, and contrast-enhanced magnetic resonance imaging. Arthritis Rheum 42:1232–1245
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Unlu, Z., Orguc, S., Ovali, G.Y. et al. Magnetic resonance imaging findings in a case of remitting seronegative symmetrical synovitis with pitting edema. Clin Rheumatol 24, 648–651 (2005). https://doi.org/10.1007/s10067-005-1127-4
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DOI: https://doi.org/10.1007/s10067-005-1127-4