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Establishment of a biorepository for migraine research: the experience of Interinstitutional Multidisciplinary BioBank (BioBIM)

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Abstract

The development of Biobanks and recent advances in molecular biology have enhanced the possibility to accelerate translational research studies. The Interinstitutional Multidisciplinary BioBank (BioBIM) is organized in a large healthy donors collection and pathology-based biobanks with the aim to provide a service for development of interdisciplinary studies. A new pathology-based biobank has been organized to specifically collect biospecimen from patients affected by migraine, with the final goal to centralize data, collect blood, plasma, serum, DNA and RNA of patients with this disease. The BioBIM is fully equipped for the automation of sampling/processing, storage and tracking of biospecimens. Standard Operating Procedures have been developed for processing and storage phases as well as archive of clinical data. The availability of biospecimens and clinical data will constitute a resource for various research projects.

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Acknowledgments

We wish to thank Barbara Leone, Dario Marcheggiani and Vincenzino Perrone for their excellent technical assistance. This study was partially supported by Grant MERIT RBNE08NKH7 to San Raffaele Foundation (http://www.fondazionesanraffaele.com/).

Conflict of interest

The authors declare no conflict of interest.

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Authors and Affiliations

  1. Interinstitutional Multidisciplinary BioBank (BioBIM), Department of Laboratory Medicine and Advanced Biotechnologies, IRCCS San Raffaele Pisana, Via Della Pisana 235, 00163, Rome, Italy

    Raffaele Palmirotta, Giorgia Ludovici, Maria Laura De Marchis, Antonella Spila, Patrizia Ferroni, David Della-Morte & Fiorella Guadagni

  2. Headache and Pain Unit, Department of Neurological, Motor and Sensorial Sciences, IRCCS San Raffaele Pisana, Via Della Pisana 235, 00163, Rome, Italy

    Piero Barbanti, Gabriella Egeo, Cinzia Aurilia & Luisa Fofi

  3. Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA

    David Della-Morte

Authors
  1. Raffaele Palmirotta
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  2. Piero Barbanti
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  3. Giorgia Ludovici
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  4. Gabriella Egeo
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  5. Cinzia Aurilia
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  6. Luisa Fofi
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  7. Maria Laura De Marchis
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  8. Antonella Spila
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  9. Patrizia Ferroni
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  10. David Della-Morte
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  11. Fiorella Guadagni
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Corresponding author

Correspondence to Raffaele Palmirotta.

Additional information

R. Palmirotta and P. Barbanti contributed equally to this study.

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Palmirotta, R., Barbanti, P., Ludovici, G. et al. Establishment of a biorepository for migraine research: the experience of Interinstitutional Multidisciplinary BioBank (BioBIM). Neurol Sci 34, 1659–1663 (2013). https://doi.org/10.1007/s10072-013-1308-x

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  • DOI: https://doi.org/10.1007/s10072-013-1308-x

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