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Measurement of carotid pulse wave velocity using ultrafast ultrasound imaging in hypertensive patients

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Abstract

Purpose

The study aimed to assess the utility of ultrafast ultrasound imaging for evaluation of carotid pulse wave velocity (PWV) in newly diagnosed hypertension patients.

Methods

This prospective non-randomized study enrolled 90 hypertensive patients in our hospital from September to December 2013 as a hypertension group. An age- and sex-matched cohort of 50 healthy adults in our hospital from September to December 2013 was also included in the study as a control group. Carotid PWV at the beginning and at the end of systole (PWV-BS and PWV-ES, respectively) and intima-media thickness (IMT) were measured by ultrafast ultrasound imaging technology. The associations of PWV-BS, PWV-ES, and IMT with hypertension stage were evaluated by Spearman correlation analysis.

Results

PWV-BS and PWV-ES in the hypertension group were significantly elevated compared with those in control group. Different hypertension stages significantly differed in PWV-BS and PWV-ES. PWV-BS and PWV-ES appeared to increase with the hypertension stage. Moreover, IMT, PWV-BS, and PWV-ES were positively correlated with the hypertension stage in hypertensive patients.

Conclusion

Ultrafast ultrasound imaging was a valid and convenient method for the measurement of carotid PWV in hypertensive patients. Ultrafast ultrasound imaging might be recommended as a promising alternative method for early detection of arterial abnormality in clinical practice.

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Author information

Authors and Affiliations

  1. Department of Ultrasound, The Second Affiliated Hospital, Medical School of Xi’an Jiaotong University, No. 157, W. Fifth Road, Xincheng District, Xi’an, 710004, China

    Xiaopeng Li, Jue Jiang, Hong Zhang, Hua Wang, Donggang Han, Qi Zhou, Ya Gao, Shanshan Yu & Yanhua Qi

Authors
  1. Xiaopeng Li
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  2. Jue Jiang
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  3. Hong Zhang
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  4. Hua Wang
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  5. Donggang Han
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  6. Qi Zhou
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  7. Ya Gao
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  8. Shanshan Yu
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  9. Yanhua Qi
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Corresponding author

Correspondence to Qi Zhou.

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Conflict of interest

None.

Ethical statements

The study was approved by the medical ethics committee of the Second Affiliated Hospital of Xi’an Jiaotong University, and written informed consent was received from each participant.

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Cite this article

Li, X., Jiang, J., Zhang, H. et al. Measurement of carotid pulse wave velocity using ultrafast ultrasound imaging in hypertensive patients. J Med Ultrasonics 44, 183–190 (2017). https://doi.org/10.1007/s10396-016-0755-4

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  • DOI: https://doi.org/10.1007/s10396-016-0755-4

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