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Kinematic and Kinetic Interactions During Normal and ACL-Deficient Gait: A Longitudinal In Vivo Study

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Abstract

The interactions between different tissues within the knee joint and between different kinematic DOF and joint flexion during normal gait were investigated. These interactions change following ACL transection, in both short (4 weeks) and long (20 weeks) term. Ten skeletally mature sheep were used in control (N = 5) and experimental (N = 5) groups. The 6-DOF stifle joint motion was first measured during normal gait. The control group were then euthanized and mounted on a unique robotic testing platform for kinetic measurements. The experimental group underwent ACL transection surgery, and kinematics measurements were repeated 4 and 20 weeks post-operatively. The experimental group were then euthanized and underwent kinetic assessment using the robotic system. Results indicated significant couplings between joint flexion vs. abduction and internal tibial rotation, as well as medial, anterior, and superior tibial translations during both normal and ACL-deficient gait. Distinct kinetic interactions were also observed between different tissues within the knee joint. Direct relationships were found between ACL vs. LM/MM, and PCL vs. MCL loads during normal gait; inverse relationships were detected between ACL vs. PCL and PCL vs. LM/MM loads. These kinetic interaction patterns were considerably altered by ACL injury. Significant inter-subject variability in joint kinematics and tissue loading patterns during gait was also observed. This study provides further understanding of the in vivo function of different tissues within the knee joint and their couplings with joint kinematics during normal gait and over time following ACL transection.

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Abbreviations

DOF:

Degree of freedom

ACL:

Anterior cruciate ligament

LM:

Lateral meniscus

MM:

Medial meniscus

PCL:

Posterior cruciate ligament

MCL:

Medial collateral ligament

LCL:

Lateral collateral ligament

MRI:

Magnetic resonance imaging

ISL:

Instrumented spatial linkage

ATT:

Anterior tibial translation

OA:

Osteoarthritis

AA:

Abduction–adduction

AP:

Anterior–posterior

IE:

Internal–external

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Acknowledgments

Canadian Institutes of Health Research (CIHR), Alberta Innovates Health Solutions (AIHS), Natural Sciences and Engineering Research Council of Canada –Collaborative Research and Training Experience (NSERC-CREATE).

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There are no conflicts of interest.

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Authors and Affiliations

  1. McCaig Institute for Bone and Joint Health, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada

    Mohammad Atarod, Cyril B. Frank & Nigel G. Shrive

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  1. Mohammad Atarod
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  2. Cyril B. Frank
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  3. Nigel G. Shrive
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Correspondence to Mohammad Atarod.

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Associate Editor Michael R. Torry oversaw the review of this article.

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Atarod, M., Frank, C.B. & Shrive, N.G. Kinematic and Kinetic Interactions During Normal and ACL-Deficient Gait: A Longitudinal In Vivo Study. Ann Biomed Eng 42, 566–578 (2014). https://doi.org/10.1007/s10439-013-0914-3

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  • DOI: https://doi.org/10.1007/s10439-013-0914-3

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