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Multiple Complex Developmental Disorder Delineated from PDD-NOS

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Abstract

The objective of this study was to identify behavioral differences between children with multiple complex developmental disorder (MCDD) and those with pervasive developmental disorder-not otherwise specified (PDD-NOS). Twenty-five children (6–12 years) with MCDD and 86 children with PDD-NOS were compared with respect to psychiatric co-morbidity, psychotic thought problems and social contact problems using the child behavior checklist/4–18, the Dutch version of the diagnostic interview schedule for children—Version IV, the child and adolescent functional assessment scale, and the autism diagnostic observation schedule-generic. MCDD was associated with anxiety disorders, disruptive behavior, and psychotic thought problems. PDD-NOS was associated with deficits in social contact. MCDD differs from autistic disorder, and can also be delineated from PDD-NOS.

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References

  • Achenbach, T. M. (1991). Manual for the child behavior checklist/4–18 and 1991 profile. Burlington: University of Vermont, Department of Psychiatry.

    Google Scholar 

  • Ad-Dab’bagh, Y., & Greenfield, B. (2001). Multiple complex developmental disorder: the “multiple and complex” evolution of the “childhood borderline syndrome” construct. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 954–964.

    Article  PubMed  Google Scholar 

  • American Psychiatric Association (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: Author.

    Google Scholar 

  • American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.

    Google Scholar 

  • Buitelaar, J. K., & Van der Gaag, R. J. (1998). Diagnostic rules for children with PDD-NOS and multiple complex developmental disorder. Journal of Child Psychology and Psychiatry, 39, 911–919.

    Article  PubMed  Google Scholar 

  • Buitelaar, J. K., Van der Gaag, R. J., Klin, A., & Volkmar, F. R. (1999). Exploring the boundaries of pervasive developmental disorder not otherwise specified: Analyses of data from the DSM-IV autistic disorder field trial. Journal of Autism and Developmental Disorders, 29, 33–43.

    Article  PubMed  Google Scholar 

  • Byerly, M., Goodman, W., Acholonu, W., Bugno, R., & Rush, A. J. (2005). Obsessive compulsive symptoms in schizophrenia: Frequency and clinical features. Schizophrenia Research, 76, 309–316.

    Article  PubMed  Google Scholar 

  • Cicchetti, D. V., & Sparrow, S. A. (1981). Developing criteria for establishing interrater reliability of specific items: Applications to assessment of adaptive behavior. American Journal of Mental Deficiency, 86, 127–137.

    PubMed  Google Scholar 

  • Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Hillsdale: Lawrence Erlbaum.

    Google Scholar 

  • Cohen, D. J., Paul, R., & Volkmar, F. R. (1986). Issues in the classification of pervasive developmental disorders: Toward DSM-IV. Journal of the American Academy of Child and Adolescent Psychiatry, 25, 213–220.

    Google Scholar 

  • Dahl, E. K., Cohen, D. J., & Provence, S. (1986). Clinical and multivariate approaches to the nosology of pervasive developmental disorders. Journal of the American Academy of Child Psychiatry, 25, 170–180.

    Article  PubMed  Google Scholar 

  • De Bruin, E. I., Verheij, F., & Ferdinand, R. F. (2006). WISC-R subtest but no overall VIQ–PIQ difference in Dutch children with PDD-NOS. Journal of Abnormal Child Psychology, 34, 263–271.

    Article  PubMed  Google Scholar 

  • Eisen, J. L., & Rasmussen, S. A. (1993). Obsessive compulsive disorder with psychotic features. Journal of Clinical Psychiatry, 54, 373–379.

    PubMed  Google Scholar 

  • Ferdinand, R. F., & Van der Ende, J. (1998). Diagnostic interview schedule for children IV. Parent-version. Rotterdam, The Netherlands: Erasmus University, Department of Child and Adolescent Psychiatry.

    Google Scholar 

  • Ganesan, V., Kumar, T. C., & Khanna, S. (2001). Obsessive-compulsive disorder and psychosis. Canadian Journal of Psychiatry, 46, 750–754.

    Google Scholar 

  • Hodges, K. (1997). Child and adolescent functional assessment scale manual for training coordinators, clinical administrators, and data managers. Ann Harbor, MI: Author; Ypsilanti, MI: Eastern Michigan University, Department of Psychology.

  • Hodges, K., & Wong, M. M. (1996). Psychometric characteristics of a multidimensional measure to assess impairment: The child and adolescent functional assessment scale. Journal of Child and Family Studies, 5, 445–467.

    Article  Google Scholar 

  • Lord, C., Rutter, M., DiLavore, P. C., & Risi, S. (1999). Autism diagnostic observation schedule-WPS (ADOS-WPS). Los Angeles, CA: Western Psychological Services.

    Google Scholar 

  • McConaughy, S. H., & Achenbach, T. M. (2001). Manual for the semistructured clinical interview for children and adolescents (2nd ed.). Burlington, VT: University of Vermont, Research Center for Children, Youth, and Families.

    Google Scholar 

  • Petti, T. A., & Vela, R. M. (1990a). Borderline disorders of childhood: An overview. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 327–337.

    Article  Google Scholar 

  • Petti, T. A., & Vela, R. M. (1990b). Borderline disorders of childhood: An overview. Journal of the American Academy of Child and Adolescent Psychiatry, 38, 327–337.

    Article  Google Scholar 

  • Rea, L. M., & Parker, R. A. (1992). Designing and conducting survey research. San Francisco: Jossey-Bass.

    Google Scholar 

  • Schwab-Stone, M. E., Fisher, P., Piacentini, J., Shaffer, D., Davies, M., & Briggs, M. (1993). The diagnostic interview schedule for children-revised version (DISC-R): II. Test–retest reliability, 32, 651–657.

    Google Scholar 

  • Shaffer, D., Fisher, P., Dulcan, M. K., Davies, M., Piacentini, J., Schwab-Stone, M. E., et al. (1996). The NIMH diagnostic interview schedule for children Version 2.3 (DISC-2.3): Description, acceptability, prevalence rates, and performance in the MECA study. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 865–877.

    Article  PubMed  Google Scholar 

  • Shaffer, D., Fisher, P., & Lucas, C. P. (1998). NIMH DISC-IV. Diagnostic interview schedule for children. Parent-informant. New York: Columbia University.

    Google Scholar 

  • Shaffer, D., Fisher, P., Lucas, C. P., Dulcan, M. K., & Schwab-Stone, M. E. (2000). NIMH diagnostic interview schedule for children Version IV (NIMH DISC-IV): Description, differences from previous versions, and reliability of some common diagnoses. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 28–38.

    Article  PubMed  Google Scholar 

  • Shaffer, D., Schwab-Stone, M. E., Fisher, P., Cohen, P., Piacentini, J., Davies, M., et al. (1993). The diagnostic interview schedule for children-revised Version (DISC-R): I. Preparation, field testing, interrater reliability, and acceptability. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 643–650.

    Article  PubMed  Google Scholar 

  • Towbin K. E. (1997). Pervasive developmental disorder not otherwise specified. In D. J. Cohen & F. R. Volkmar (Eds.), Handbook of autism and pervasive developmental disorders (pp. 123–147). New York: Wiley.

    Google Scholar 

  • Towbin, K. E., Dykens, E. M., Pearson, G. S., & Cohen, D. J. (1993). Conceptualizing “borderline syndrome of childhood” and “childhood schizophrenia” as a developmental disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 775–782.

    Article  PubMed  Google Scholar 

  • Van der Gaag, R. J., Buitelaar, J., Van den Ban, E., Bezemer, M., & Van Engeland, H. (1995). A controlled multivariate chart review of multiple complex developmental disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 34, 1096–1106.

    Article  PubMed  Google Scholar 

  • Volkmar, F. R., Klin, A., & Cohen, D. J. (1997). Diagnosis and classification of autism and related conditions: consensus and issues. In D. J. Cohen & F. R. Volkmar (Eds.), Handbook of autism and pervasive developmental disorders (pp. 1–40). New York: Wiley.

    Google Scholar 

  • Volkmar, F. R., Klin, A., Siegel, B., Szatmari, P., Lord, C., Campbell, M., et al. (1994). Field trial for autistic disorder in DSM-IV. American Journal of Psychiatry, 151, 1361–1367.

    PubMed  Google Scholar 

  • Volkmar, F. R., & Wiesner, L. A. (2004). Getting a diagnosis. In F. R. Volkmar & L. A. Wiesner (Eds.), Healthcare for children on the autism spectrum: A guide to medical, nutritional, and behavioral issues (pp. 29–51). Bethesda, MD: Woodbine House.

    Google Scholar 

  • Wechsler, D. (1974). Wechsler intelligence scale for children-revised manual. New York: The Psychological Corporation.

    Google Scholar 

  • WISC-R Projectgroep: Van Haasen, P. P., De Bruyn, E. E. J., Pijl, Y. J., Poortinga, Y. H., Spelberg, H. C., Van der Steene, G., et al. (1986). WISC-R, Wechsler intelligence scale for children-revised, Nederlandse uitgave. Deel I. Lisse: Swets & Zeitlinger.

  • World Health Organisation (1993). International classification of diseases and disorders (ICD-10). Geneva: WHO.

    Google Scholar 

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Correspondence to Robert F. Ferdinand.

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de Bruin, E.I., de Nijs, P.F.A., Verheij, F. et al. Multiple Complex Developmental Disorder Delineated from PDD-NOS. J Autism Dev Disord 37, 1181–1191 (2007). https://doi.org/10.1007/s10803-006-0261-4

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