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How good are we at modeling implantation?

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  • 08 May 2020

    The original article unfortunately contained a mistake. The name of the author should be Lusine Aghajanova instead of Aghajanova Lusine.

References

  1. Macklon NS, Geraedts JP, Fauser BC. Conception to ongoing pregnancy: the ‘black box’ of early pregnancy loss. Hum Reprod Update 2002;8(4):333–343. Epub 2002/09/11. doi: https://doi.org/10.1093/humupd/8.4.333.

  2. Teklenburg G, Macklon NS. Review: in vitro models for the study of early human embryo-endometrium interactions. Reprod Sci. 2009;16(9):811–8. Epub 2009/04/28. https://doi.org/10.1177/1933719109334966.

    Article  PubMed  Google Scholar 

  3. Landgren BM, Johannisson E, Stavreus-Evers A, Hamberger L, Eriksson H. A new method to study the process of implantation of a human blastocyst in vitro. Fertil Steril. 1996;65(5):1067–70. Epub 1996/05/01. https://doi.org/10.1016/s0015-0282(16)58291-0.

    Article  CAS  PubMed  Google Scholar 

  4. Kliman HJ, Feinberg RF, Haimowitz JE. Human trophoblast-endometrial interactions in an in vitro suspension culture system. Placenta. 1990;11(4):349–367. Epub 1990/07/01. doi: https://doi.org/10.1016/s0143-4004(05)80226-7.

  5. Galan A, O’Connor JE, Valbuena D, Herrer R, Remohi J, Pampfer S, et al. The human blastocyst regulates endometrial epithelial apoptosis in embryonic adhesion. Biol Reprod. 2000;63(2):430–9.

    Article  CAS  Google Scholar 

  6. Bentin-Ley U, Pedersen B, Lindenberg S, Larsen JF, Hamberger L, Horn T. Isolation and culture of human endometrial cells in a three-dimensional culture system. J Reprod Fertil. 1994;101(2):327–32.

    Article  CAS  Google Scholar 

  7. Boggavarapu NR, Berger C, von Grothusen C, Menezes J, Gemzell-Danielsson K, Lalitkumar PG. Effects of low doses of mifepristone on human embryo implantation process in a three-dimensional human endometrial in vitro co-culture system. Contraception. 2016;94(2):143–51. Epub 2016/03/24. https://doi.org/10.1016/j.contraception.2016.03.009.

    Article  CAS  PubMed  Google Scholar 

  8. Berger C, Boggavarapu NR, Menezes J, Lalitkumar PG, Gemzell-Danielsson K. Effects of ulipristal acetate on human embryo attachment and endometrial cell gene expression in an in vitro co-culture system. Hum Reprod 2015;30(4):800–811. Epub 2015/03/06. doi: https://doi.org/10.1093/humrep/dev030.

  9. Popovici RM, Betzler NK, Krause MS, Luo M, Jauckus J, Germeyer A, et al. Gene expression profiling of human endometrial-trophoblast interaction in a coculture model. Endocrinology. 2006;147(12):5662–75. Epub 2006/09/02. https://doi.org/10.1210/en.2006-0916.

    Article  CAS  PubMed  Google Scholar 

  10. White MD, Zenker J, Bissiere S, Plachta N. Instructions for assembling the early mammalian embryo. Dev Cell 2018;45(6):667–679. Epub 2018/06/20. doi: https://doi.org/10.1016/j.devcel.2018.05.013.

  11. Zheng Y, Xue X, Shao Y, Wang S, Esfahani SN, Li Z, et al. Controlled modelling of human epiblast and amnion development using stem cells. Nature. 2019;573(7774):421–5. Epub 2019/09/13. https://doi.org/10.1038/s41586-019-1535-2.

    Article  CAS  PubMed  Google Scholar 

  12. Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T, Saitou M. A developmental coordinate of pluripotency among mice, monkeys and humans. Nature. 2016;537(7618):57–62. Epub 2016/08/25. doi: https://doi.org/10.1038/nature19096.

  13. Teklenburg G, Salker M, Molokhia M, Lavery S, Trew G, Aojanepong T, Mardon HJ, Lokugamage AU, Rai R, Landles C, Roelen BA, Quenby S, Kuijk EW, Kavelaars A, Heijnen CJ, Regan L, Brosens JJ, Macklon NS. Natural selection of human embryos: decidualizing endometrial stromal cells serve as sensors of embryo quality upon implantation. PLoS One. 2010;5(4):e10258. Epub 2010/04/28. doi: https://doi.org/10.1371/journal.pone.0010258. PubMed PMID: 20422011; PMCID: PMC2858159.

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Lusine, A. How good are we at modeling implantation?. J Assist Reprod Genet 37, 17–19 (2020). https://doi.org/10.1007/s10815-019-01667-8

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  • DOI: https://doi.org/10.1007/s10815-019-01667-8

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