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Molecular epidemiology of Newcastle disease viruses in Vietnam

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Abstract

Newcastle disease virus (NDV) causes significant economic losses to the poultry industry in Southeast Asia. In the present study, 12 field isolates of NDV were recovered from dead village chickens in Vietnam between 2007 and 2012, and were characterized. All the field isolates were classified as velogenic. Based on the sequence analysis of the F variable region, two distinct genetic groups (Vietnam genetic groups G1 and G2) were recognized. Phylogenetic analysis revealed that all the 12 field isolates fell into the class II genotype VII cluster. Ten of the field isolates, classified as Vietnam genetic group G1, were closely related to VIIh viruses that had been isolated from Indonesia, Malaysia, and Cambodia since the mid-2000s, while the other two field isolates, of Vietnam genetic group G2, clustered with VIId viruses, which were predominantly circulating in China and Far East Asia. Our results indicate that genotype VII viruses, especially VIIh viruses, are predominantly responsible for the recent epizootic of the disease in Vietnam.

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Acknowledgments

This work was fully supported by the Animal, Plant, and Fisheries Quarantine and Inspection Agency, Republic of Korea (grant no. M-AD15-2011-13-02).

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Authors and Affiliations

  1. Avian Diseases Division, Animal and Plant Quarantine Agency, 175 Anyang-ro, Manan-gu, Anyang, Gyeonggi, 430-757, Republic of Korea

    Kang-Seuk Choi, Soo-Jeong Kye, Ji-Ye Kim, Youn-Jeong Lee, Jun-Gu Choi, Hyun-Mi Kang, Kwang-Il Kim, Byung-Min Song & Hee-Soo Lee

  2. National Center for Veterinary Diagnosis, Department of Animal Health, 11/78 Giai Phong 12 St. Dong Da disk, Hanoi, Vietnam

    Thanh Long To & Dang Tho Nguyen

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  1. Kang-Seuk Choi
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Correspondence to Kang-Seuk Choi.

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Choi, KS., Kye, SJ., Kim, JY. et al. Molecular epidemiology of Newcastle disease viruses in Vietnam. Trop Anim Health Prod 46, 271–277 (2014). https://doi.org/10.1007/s11250-013-0475-3

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