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Association between osteoporosis and sleep duration in healthy middle-aged and elderly adults: a large-scale, cross-sectional study in Japan

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Abstract

Study objectives

This study aims to explore the association between osteoporosis and nightly sleep duration among adult outpatients.

Design

This is a large-scale, retrospective cross-sectional study.

Setting

The setting was in a preventive medicine health center at a general community hospital in Tokyo, Japan.

Participants

There were 19,321 healthy individuals (≥50 years old) who underwent annual general health checkup between January and December 2008.

Measurements

The participants were divided into four groups according to their self-reported average nightly sleep duration (<6, 6–6.9, 7–7.9, and >8 h). Radial bone mineral density was measured using dual-energy X-ray absorptiometry, and T-score was compared to young adult mean to diagnose osteoporosis. Multivariate logistic regression was used to explore the association between sleep duration and osteoporosis.

Results

The mean age of the participants was 60.9 years (standard deviation [SD], 7.9) and 48.0% were female. The prevalence of osteoporosis was 8.0% (95% confidence interval [CI] = 7.6–8.4%). Those with sleep duration of >8 h were more likely to have osteoporosis (odds ratio [OR] = 1.35; 95% CI = 1.06–1.73) than those with short sleep duration (<6 h).

Conclusion

Those individuals with self-reported sleep duration of more than 8 h (long sleepers) appear to have higher odds of osteoporosis compared to the progressively shorter sleepers.

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Acknowledgements

We gratefully acknowledge Dr. Toshiko Kawakita for contributing data of the Center for Preventive Medicine at St. Luke’s International Hospital and thank Mina Shapiro, RN for editing the manuscript.

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Authors and Affiliations

  1. Division of General Internal Medicine, Department of Medicine, St. Luke’s International Hospital, Tokyo, Japan

    Daiki Kobayashi, Osamu Takahashi, Gautam A. Deshpande & Tsuguya Fukui

  2. Department of Internal Medicine, University of Hawaii, Honolulu, HI, USA

    Gautam A. Deshpande

  3. Department of Clinical Research and Informatics, National Centre for Global Health and Medicine, Tokyo, Japan

    Takuro Shimbo

Authors
  1. Daiki Kobayashi
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  2. Osamu Takahashi
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  3. Gautam A. Deshpande
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  4. Takuro Shimbo
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  5. Tsuguya Fukui
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Corresponding author

Correspondence to Daiki Kobayashi.

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Kobayashi, D., Takahashi, O., Deshpande, G.A. et al. Association between osteoporosis and sleep duration in healthy middle-aged and elderly adults: a large-scale, cross-sectional study in Japan. Sleep Breath 16, 579–583 (2012). https://doi.org/10.1007/s11325-011-0545-6

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  • DOI: https://doi.org/10.1007/s11325-011-0545-6

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