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The influence of nasal abnormalities in adherence to continuous positive airway pressure device therapy in obstructive sleep apnea patients

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Abstract

Background

The few studies that examine the effect of nasal abnormalities on continuous positive airway pressure device (CPAP) adherence are controversial. The aim of this study was to evaluate the contribution of nasal abnormalities in CPAP adherence.

Methods

We included patients with moderate to severe OSA. The patients were submitted to rhinoscopy, nasofibroscopy, nasal inspiratory peak flow, and acoustic rhinometry. The patients who used a CPAP for 4 h or more per night for at least 70 % of the nights over a 6-month period were considered to have good adherence.

Results

Thirty-four patients finished the study. Eleven (33.4 %) were female and 23 (67.6 %) were male. Sixteen (47.1 %) patients had good adherence. The body mass index (p = 0.030), neck circumference (p = 0.006), and apnea–hypopnea index (p = 0.032) were higher, and the oxyhemoglobin saturation minimum was lower (p = 0.041) in the good adherence group. Nasal parameters showed no differences between good and poor adherence groups. In Spearman’s correlation, surprisingly, there was a negative correlation between the highest number of hours of CPAP use with smaller values of nasal minimal cross-sectional areas in the supine position (r, 0.375; p = 0.029). In the linear regression model, the nasal findings that predicted increased of the CPAP use were the following: lower scores of nasal symptoms (p = 0.007) and lower nasal volume in supine position (p = 0.001).

Conclusions

The majority of the nasal parameters evaluated in this study did not influence CPAP adherence.

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Acknowledgments

This study was supported by AFIP, FAPESP/CEPID, and CNPq.

Conflict of interest

The authors had no conflicts of interest.

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Authors and Affiliations

  1. Disciplina de Medicina e Biologia do Sono-Departamento de Psicobiologia, Universidade Federal de São Paulo, Rua Napoleao de Barros, 925, Vila Clementino, São Paulo, SP, Brazil, 04024-002

    Fernanda Louise Martinho Haddad, Luciane Mello-Fujita, Fátima Dumas Cintra, Sérgio Tufik & Lia Bittencourt

  2. Departamento de Otorrinolaringologia e cirurgia de cabeça e Pescoço, Universidade Federal de São Paulo, São Paulo, Brazil

    Fernanda Louise Martinho Haddad, Tatiana de Aguiar Vidigal & Luiz Carlos Gregório

Authors
  1. Fernanda Louise Martinho Haddad
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  2. Tatiana de Aguiar Vidigal
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  3. Luciane Mello-Fujita
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  4. Fátima Dumas Cintra
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  5. Luiz Carlos Gregório
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  6. Sérgio Tufik
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  7. Lia Bittencourt
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Corresponding author

Correspondence to Fernanda Louise Martinho Haddad.

Additional information

This study was performed at the Universidade Federal de São Paulo, Brazil and was presented as an oral presentation at the 25th Annual Meeting of the Associated Professional Sleep Societies, Minneapolis, USA, 13 to 15 June 2011. Sleep. 2011; 34 (Abstract Suppl.): p. A118. (Abstract 0337).

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Haddad, F.L.M., Vidigal, T.A., Mello-Fujita, L. et al. The influence of nasal abnormalities in adherence to continuous positive airway pressure device therapy in obstructive sleep apnea patients. Sleep Breath 17, 1201–1207 (2013). https://doi.org/10.1007/s11325-013-0824-5

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  • DOI: https://doi.org/10.1007/s11325-013-0824-5

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