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Positive effects of resistance training in frail elderly patients with dementia after long-term physical restraint

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Abstract

This study investigated the effects of a multicomponent exercise intervention on muscle strength, incidence of falls and functional outcomes in frail elderly patients with dementia after long-term physical restraint, followed by 24 weeks of training cessation. Eighteen frail elderly patients with mild dementia (88.1 ± 5.1 years) performed a multicomponent exercise program, which consisted of 4 weeks of walking, balance and cognitive exercises, followed by 4 weeks of resistance exercise performed twice weekly [8–12 repetitions at 20–50 % of the one-repetition maximum (1RM)], combined with walking, balance and cognitive exercises. Before and after training, as well as after 24 weeks of training cessation, strength outcomes, Barthel Index, balance, gait ability, rise from a chair ability, dual task performance, incidence of falls and Mini-Mental State Examination were assessed. After the first 4 weeks of training, there was a significant improvement only in the balance test, whereas no additional changes were observed. However, after the second part of the training, the participants required significantly less time for the time-up-and-go test (P < 0.05), and improved the isometric hand grip, hip flexion and knee extension strength, as well as the leg press 1RM (P < 0.01). A significant reduction was also observed in the incidence of falls (P < 0.01). After 24 weeks of training cessation, abrupt decreases were observed in nearly all of the physical outcomes (P < 0.05). The exercise intervention improved strength, balance and gait ability in frail elderly patients with dementia after long-term physical restraint, and these benefits were lost after training cessation.

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Acknowledgements

This work was supported in part by the Spanish Department of Health and Institute Carlos III of the Government of Spain [Spanish Net on Aging and frailty; (RETICEF)], Department of Health of the Government of Navarre and Economy and Competitivity Department of the Government of Spain, under grants numbered RD12/043/0002, 87/2010, and DEP2011-24105, respectively. This project is also funded in part by the European Commision (FP7-Health, Project reference: 278803).

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Authors and Affiliations

  1. Department of Health Sciences, Public University of Navarre, Campus of Tudela Av. de Tarazona s/n, 31500, Tudela, Navarra, Spain

    Eduardo L. Cadore, Ana B. Bays Moneo & Mikel Izquierdo

  2. Real Casa de Misericordia, Tudela, Navarra, Spain

    Marta Martinez Mensat & Andrea Rozas Muñoz

  3. Division of Geriatric Medicine, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain

    Alvaro Casas-Herrero

  4. Division of Geriatric Medicine, University Hospital of Getafe, Madrid, Spain

    Leocadio Rodriguez-Mañas

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  1. Eduardo L. Cadore
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  2. Ana B. Bays Moneo
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  4. Andrea Rozas Muñoz
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  5. Alvaro Casas-Herrero
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  6. Leocadio Rodriguez-Mañas
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  7. Mikel Izquierdo
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Correspondence to Mikel Izquierdo.

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Cadore, E.L., Moneo, A.B.B., Mensat, M.M. et al. Positive effects of resistance training in frail elderly patients with dementia after long-term physical restraint. AGE 36, 801–811 (2014). https://doi.org/10.1007/s11357-013-9599-7

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  • DOI: https://doi.org/10.1007/s11357-013-9599-7

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