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Ultrasound speckle tracking imaging contributes to early diagnosis of impaired left ventricular systolic function in patients with type 2 diabetes mellitus

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Summary

To investigate the value of ultrasound speckle tracking imaging (STI) in the assessment of the short-axis and long-axis systolic function of the left ventricle (LV) in patients with type 2 diabetes mellitus (DM), 100 subjects with normal ejection fraction were studied, including 41 patients with DM only (DM group), 22 patients with both DM and left ventricular hypertrophy (DH group), and 37 healthy subjects (control group). Left ventricle systolic function in the long axis defined as longitudinal strain, and that in the short axis defined as radial strain, apical and basal LV rotations, and LV twist were assessed respectively. The results showed that average peak strain in the long axis at basal, middle and apical levels, and global peak strain were significantly decreased in the patient groups when compared with the control group (P<0.001 for each). The parameters in DH group were significantly lower than those in DM group (P<0.01 for each). There were no significant differences in average radial peak strain in the short axis at different levels, and global peak strain among the three groups (P>0.05). Apical and basal LV rotations, and LV twist were greater in the patient groups than in the control group (P<0.01 for each). Basal LV rotation and LV twist were greater in DH group than those in DM group (P<0.01). It was concluded that STI may be used to identify early abnormalities in patients with type 2 DM that have normal left ventricular systolic function.

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Authors and Affiliations

  1. Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Hubei Provincial Key Laboratory of Molecular Imaging, Wuhan, 430022, China

    Hong Ma  (马 红), Mingxing Xie  (谢明星), Jing Wang  (王 静), Qing Lü  (吕 清), Xinfang Wang  (王新房), Xiaofang Lu  (卢晓芳), Yali Yang  (杨亚利) & Lijun Hu  (胡莉君)

  2. Department of Special Diagnosis, Henan Provincial Corps Hospital, Chinese People’s Armed Police Force, Zhengzhou, 450052, China

    Hong Ma  (马 红)

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  1. Hong Ma  (马 红)
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  2. Mingxing Xie  (谢明星)
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  3. Jing Wang  (王 静)
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  4. Qing Lü  (吕 清)
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  5. Xinfang Wang  (王新房)
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  6. Xiaofang Lu  (卢晓芳)
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  7. Yali Yang  (杨亚利)
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  8. Lijun Hu  (胡莉君)
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Additional information

Hong MA, female, born in 1965, Ph.D., Associate Professor

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Ma, H., Xie, M., Wang, J. et al. Ultrasound speckle tracking imaging contributes to early diagnosis of impaired left ventricular systolic function in patients with type 2 diabetes mellitus. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 28, 719–723 (2008). https://doi.org/10.1007/s11596-008-0624-5

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  • DOI: https://doi.org/10.1007/s11596-008-0624-5

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