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Time Course of Blood Pressure Decrease After Bariatric Surgery in Normotensive and Hypertensive Patients

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Abstract

Background

Bariatric surgery leads to remission of several obesity-related comorbidities, including hypertension. Although antihypertensive medication use is decreased after bariatric surgery, the exact time course of decrease in blood pressure after surgery is not known.

Methods

A database of patients undergoing bariatric surgery at our institute was used to study the effect of surgery on time course of blood pressure changes. Data from surgeries performed between January 2010 and December 2012 were used.

Results

Maximum blood pressure and body weight decreases were observed at 2 weeks and 1 year after surgery, respectively. Average decrease in the mean arterial pressure (MAP) was 4.46 mmHg (61.5 ± 17.1% of maximal decrease) and 7.17 mmHg (maximum decrease) at 1 and 2 weeks after surgery, when the decrease in body weight is 22.8 ± 1.6 and 28 ± 1.4% of maximal weight loss, respectively. In hypertensive patients, MAP decreased from 98.5 ± 0.78 to 92.3 ± 1.76 and 93.1 ± 0.92 mmHg at 1 and 2 weeks post-surgery, respectively. In normotensive patients, the MAP decreased from 96.2 ± 0.79 to 88.7 ± 1.25, 90.0 ± 0.94, 86.5 ± 1.35, 88.0 ± 1.13, and 86.4 ± 2.13 mmHg at 2 weeks, 3 and 6 months, and 1 and 3 years after surgery, respectively.

Conclusions

These data demonstrate that significant decrease in MAP occurs within 2 weeks after bariatric surgery in hypertensive as well as normotensive patients. Future studies are required to investigate the weight-independent mechanisms of blood pressure decreases after bariatric surgery.

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Authors and Affiliations

  1. Department of General Surgery, Dwight D Eisenhower Army Medical Center, Fort Gordon, GA, 30905, USA

    Devon N. Hawkins, Byron J. Faler & Yong U. Choi

  2. Department of Clinical Investigation, Dwight D Eisenhower Army Medical Center, 38705 Seventh Avenue, Fort Gordon, GA, 30905, USA

    Balakrishna M. Prasad

Authors
  1. Devon N. Hawkins
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  2. Byron J. Faler
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  3. Yong U. Choi
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  4. Balakrishna M. Prasad
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Correspondence to Balakrishna M. Prasad.

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The authors declare that they have no conflict of interest.

Ethical Statement

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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For this type of study, formal consent is not required.

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Hawkins, D.N., Faler, B.J., Choi, Y.U. et al. Time Course of Blood Pressure Decrease After Bariatric Surgery in Normotensive and Hypertensive Patients. OBES SURG 28, 1845–1851 (2018). https://doi.org/10.1007/s11695-017-3091-x

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