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Availability of decontamination, elimination enhancement, and stabilization resources for the management of acute toxic exposures and poisonings in emergency departments in Malaysia

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Abstract

Acute poisoning is a common medical emergency in Malaysia. Life can be saved if the patient is diagnosed properly and receives the appropriate treatment such as gastrointestinal decontamination techniques and resources to increase poison elimination according to clinical guidelines at a reasonable time. The aims of this study were to determine the availability of decontamination, elimination enhancement, and stabilization resources for the management of acute toxic exposures and poisonings in accident and emergency departments in Malaysia, and to compare the availability of such facilities among various types of hospitals. A comparative, descriptive cross-sectional study was conducted using a structured questionnaire. Seventy-four (58.3%) out of the targeted 127 hospitals replied and completed the questionnaire. The availabilities of most items related to stabilization resources were far better in general hospitals compared to district hospitals with specialists and district hospitals without specialists. These items were mechanical ventilators (p = 0.011), non-invasive positive pressure ventilators (0.024), pacemakers (p = 0.019), and transcutaneous cardiac pacing (p < 0.001). The availability of decontamination resources varied substantially with hospital type. Nevertheless, these differences did not reach statistical significance in any of the cases, whereas sodium sulphate, sorbitol, and polyethylene glycol were almost never available. The availabilities of most items related to elimination enhancement resources were far better in general hospitals and district hospitals with specialists compared to district hospitals without specialists. These items were haemodialysis (p = 0.046), haemoperfusion (p = 0.002), haemofiltration (p = 0.002), acid diuresis (p = 0.04), peritoneal dialysis (p < 0.001), and exchange transfusion (p < 0.001). Most Malaysian hospitals have certain important immediate interventions such as gastrointestinal decontamination techniques and resources to increase poison elimination. The availabilities of most facilities were far better in the general hospitals. Coordination between the National Poison Centre in Malaysia and hospitals should be established regarding the emergency facilities for effective management of poisoning cases in each hospital in order to direct the poisoned patients to the hospital where the appropriate management resources is available.

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References

  1. Hladki W, Andres J, Trybus M, Drwila R (2007) Emergency medicine in Poland. Resuscitation 75:213–218

    Article  PubMed  Google Scholar 

  2. Derlet RW, Richards JR (2000) Overcrowding in the nation’s emergency departments: complex causes and disturbing effects. Ann Emerg Med 35:63–68

    Article  PubMed  CAS  Google Scholar 

  3. Daly FF, Little M, Murray L (2006) A risk assessment based approach to the management of acute poisoning. Emerg Med J 23:396–399

    Article  PubMed  CAS  Google Scholar 

  4. Zyoud SH, Awang R, Syed Sulaiman SA, Al-Jabi SW (2011) An analysis of the length of hospital stay after acetaminophen overdose. Hum Exp Toxicol 16:788–792

    Google Scholar 

  5. Krenzelok EP (2002) New developments in the therapy of intoxications. Toxicol Lett 127:299–305

    Article  PubMed  CAS  Google Scholar 

  6. Worthley LI (2002) Clinical toxicology: part I. Diagnosis and management of common drug overdosage. Crit Care Resusc 4:192–215

    PubMed  CAS  Google Scholar 

  7. Boyle JS, Bechtel LK, Holstege CP (2009) Management of the critically poisoned patient. Scand J Trauma Resusc Emerg Med 17:29

    Article  PubMed  Google Scholar 

  8. Seger D, Muelenbelt J (2004) Position paper: ipecac syrup. J Toxicol Clin Toxicol 42:133–143

    Article  Google Scholar 

  9. Greene S, Harris C, Singer J (2008) Gastrointestinal decontamination of the poisoned patient. Pediatr Emerg Care 24:176–186 (quiz 187–179)

    Article  PubMed  Google Scholar 

  10. Mokhlesi B, Leiken JB, Murray P, Corbridge TC (2003) Adult toxicology in critical care: part I: general approach to the intoxicated patient. Chest 123:577–592

    Article  PubMed  Google Scholar 

  11. Rajasuriar R, Awang R, Hashim SB, Rahmat HR (2007) Profile of poisoning admissions in Malaysia. Hum Exp Toxicol 26:73–81

    Article  PubMed  CAS  Google Scholar 

  12. Zyoud SH, Awang R, Sulaiman SA, Al-Jabi SW (2010) A cross-sectional observation of the factors associated with deliberate self-poisoning with acetaminophen: impact of gender differences and psychiatric intervention. Hum Psychopharmacol 25:500–508

    Article  PubMed  Google Scholar 

  13. Cummings SM, Savitz LA, Konrad TR (2001) Reported response rates to mailed physician questionnaires. Health Serv Res 35:1347–1355

    PubMed  CAS  Google Scholar 

  14. Ary D, Jacobs LC, Razavieh A, Sorensen C (2009) Introduction to research in education. Wadsworth Pub Co, Belmont

    Google Scholar 

  15. Lee S (2011) Disaster management and emergency medicine in Malaysia. West J Emerg Med 12:5–6

    Article  CAS  Google Scholar 

  16. Rasiah R, Noh A, Tumin M (2009) Privatising healthcare in Malaysia: power, policy and profits. J Contemp Asia 39:50–62

    Article  Google Scholar 

  17. Al-Sohaim SI, Awang R, Zyoud SH, Rashid SM, Hashim S (2011) Evaluate the impact of hospital types on the availability of antidotes for the management of acute toxic exposures and poisonings in Malaysia. Hum Exp Toxicol (Epub ahead of print)

  18. Lewis JR (1996) Binomial confidence intervals for small sample usability studies. In: Salvendy G, Ozok A (eds) Advances in applied ergonomics: Proceedings of the 1st International Conference on Applied Ergonomics—ICAE 1996, USA Publishing, Istanbul, pp 732–737

  19. Sauro J, Lewis JR (2005) Estimating completion rates from small samples using binomial confidence intervals: comparisons and recommendations. Human Factors and Ergonomics Society, Santa Monica, pp 2100–2104

  20. Lewis JR, Sauro J (2006) When 100% really isn’t 100%: improving the accuracy of small-sample estimates of completion rates. J usability stud 1:136–150

    Google Scholar 

  21. Richards JR, Navarro ML, Derlet RW (2000) Survey of directors of emergency departments in California on overcrowding. West J Med 172:385–388

    Article  PubMed  CAS  Google Scholar 

  22. Wetter DC, Daniell WE, Treser CD (2001) Hospital preparedness for victims of chemical or biological terrorism. Am J Public Health 91:710–716

    Article  PubMed  CAS  Google Scholar 

  23. Manley WG, Furbee PM, Coben JH, Smyth SK, Summers DE, Althouse RC, Kimble RL, Kocsis AT, Helmkamp JC (2006) Realities of disaster preparedness in rural hospitals. Disaster Manag Response 4:80–87

    Article  PubMed  Google Scholar 

  24. Ponampalam R, Anantharaman V (2003) The need for drug and poison information—the Singapore physicians’ perspective. Singap Med J 44:231–242

    CAS  Google Scholar 

  25. Ong HC, Yang CC, Deng JF (2000) Inadequate stocking of antidotes in Taiwan: is it a serious problem? J Toxicol Clin Toxicol 38:21–28

    Article  PubMed  CAS  Google Scholar 

  26. Dillman DA (1991) The design and administration of mail surveys. Annu Rev Sociol 17:225–249

    Article  Google Scholar 

  27. Dillman DA, Sangster RL, Tarnai J, Rockwood TH (1996) Understanding differences in people’s answers to telephone and mail surveys. New Dir Eval 1996:45–61

    Article  Google Scholar 

  28. Cosgrove JF, Gascoigne AD (1999) Inadequate assessment of the airway and ventilation in acute poisoning. A need for improved education? Resuscitation 40:161–164

    Article  PubMed  CAS  Google Scholar 

  29. Roy TM, Ossorio MA, Cipolla LM, Fields CL, Snider HL, Anderson WH (1989) Pulmonary complications after tricyclic antidepressant overdose. Chest 96:852–856

    Article  PubMed  CAS  Google Scholar 

  30. Marik PE (2010) Aspiration syndromes: aspiration pneumonia and pneumonitis. Hosp Pract (Minneap) 38:35–42

    Article  Google Scholar 

  31. Chyka PA, Seger D, Krenzelok EP, Vale JA (2005) Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 43:61–87

    CAS  Google Scholar 

  32. Vale JA, Kulig K (2004) Position paper: gastric lavage. J Toxicol Clin Toxicol 42:933–943

    Article  PubMed  CAS  Google Scholar 

  33. Seger D, Meulenbelt J (2004) Position paper: whole bowel irrigation. J Toxicol Clin Toxicol 42:843–854

    Article  Google Scholar 

  34. Seger D, Muelenbelt J (2004) Position paper: cathartics. J Toxicol Clin Toxicol 42:243–253

    Article  Google Scholar 

  35. Mert E, Bilgin NG (2006) Demographical, aetiological and clinical characteristics of poisonings in Mersin, Turkey. Hum Exp Toxicol 25:217–223

    Article  PubMed  Google Scholar 

  36. Cutler RE, Forland SC, Hammond PG, Evans JR (1987) Extracorporeal removal of drugs and poisons by hemodialysis and hemoperfusion. Annu Rev Pharmacol Toxicol 27:169–191

    Article  PubMed  CAS  Google Scholar 

  37. Garella S (1988) Extracorporeal techniques in the treatment of exogenous intoxications. Kidney Int 33:735–754

    Article  PubMed  CAS  Google Scholar 

  38. Greenberg MI, Jurgens SM, Gracely EJ (2002) Emergency department preparedness for the evaluation and treatment of victims of biological or chemical terrorist attack. J Emerg Med 22:273–278

    Article  PubMed  Google Scholar 

  39. Sawalha AF, Sweileh WM, Tufaha MT, Al-Jabi DY (2010) Analysis of the pattern of acute poisoning in patients admitted to a governmental hospital in Palestine. Basic Clin Pharmacol Toxicol 107:914–918

    CAS  Google Scholar 

Download references

Acknowledgments

The authors would like to thank Universiti Sains Malaysia (USM) for the financial support provided for this research. The assistance of accident and emergency department staff is gratefully acknowledged.

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Correspondence to Rahmat Awang.

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Awang, R., Al-Sohaim, S.I., Zyoud, S.H. et al. Availability of decontamination, elimination enhancement, and stabilization resources for the management of acute toxic exposures and poisonings in emergency departments in Malaysia. Intern Emerg Med 6, 441–448 (2011). https://doi.org/10.1007/s11739-011-0662-z

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