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Gestational Trophoblastic Tumours: An Update for 2014

  • Gynecologic Cancers (NS Reed, Section Editor)
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Abstract

Gestational trophoblastic disease describes a variety of pregnancy-related diseases including the premalignant conditions of a partial and complete hydatidiform mole and the malignant disorders of invasive mole, choriocarcinoma and the rare placental-site trophoblastic tumour and epithelioid trophoblastic tumour. The availability of a highly sensitive tumour marker in the form of human chorionic gonadotrophin, the chemosensitive character of the disease with effective treatment strategies and centralization of care of a rare group of diseases has resulted in excellent survival rates, which can exceed 98 %. This review gives a general overview of gestational trophoblastic disease, the most recent insights in aetiology and pathology and a summary of the different management strategies.

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Conflict of Interest

Fieke E. M. Froeling and Michael J. Seckl declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Department of Medical Oncology, Charing Cross Gestational Trophoblastic Disease Centre, Imperial College Healthcare NHS Trust and Imperial College London, Fulham Palace Road, London, W6 8RF, UK

    Fieke E. M. Froeling & Michael J. Seckl

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  1. Fieke E. M. Froeling
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  2. Michael J. Seckl
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Correspondence to Michael J. Seckl.

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This article is part of the Topical Collection on Gynecologic Cancers

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Froeling, F.E.M., Seckl, M.J. Gestational Trophoblastic Tumours: An Update for 2014. Curr Oncol Rep 16, 408 (2014). https://doi.org/10.1007/s11912-014-0408-y

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