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Endoscopy-Assisted Transoral Resection of Parapharyngeal Space Tumors: A Retrospective Analysis

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Abstract

The technique of endoscopy-assisted transoral approach (EATA) has improved greatly, which should provide a better alternative for parapharyngeal space (PPS) tumors. Here, we compared curative effects between the resection of parapharyngeal space (PPS) tumors by EATA and external approaches (EAs), including the transcervical, transparotid, and transmandibular approaches. Based on the tumors’ position and the relationship with adjacent structures, we selected 20 patients with parapharyngeal space tumor hospitalized in the Second People’s Hospital in Shenzhen from January 2008 to December 2013, which were divided into the observation group and the control group with patients’ informed consents. In the observation group, the tumors were removed solely by transoral approach under the guidance of endoscopes (EATA), while in the control group, the tumors were resected completely using an external approach (EA). We compared the total removal rate, the operation time, blood loss, postoperative pain, hospitalized time, complication rate, scar, and recurrence between the two groups. All the tumors were completely removed and patients were followed up for 6 months–5 years with no recurrence in either group. There was no significant difference regarding total removal rate, operation time, complication rate, and recurrence rate between the two groups (P > 0.05). However, significant differences were observed in blood loss, hospitalized time, and postoperative pain between the two groups (P < 0.05). PPS tumors could be completely removed by both EATA and EA. However, EATA has advantages of shortened hospitalized time, alleviated blood loss and postoperative pain level, and preservation of facial cosmetic.

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Acknowledgments

We thank Shenzhen medical research project (201302237) and Shenzhen knowledge creativity project (JCYJ2013401113155027, JCYJ20130401113503369, JCYJ20140414170821293) to support our research.

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Authors and Affiliations

  1. Department of ENT, QiLu Hospital, Shandong University, 107#,Wenhua Xi Road, Jinan, 250012, People’s Republic of China

    Xiaobin Wang & Xinliang Pan

  2. Department of ENT, Shenzhen The Second People’s Hospital, 3002#, Sungang Xi Road, Shenzhen, 518035, People’s Republic of China

    Xiaobin Wang, Yongtian Lu & Huanji Sun

  3. Department of ENT, The First Affiliated Hospital of Shenzhen University, 3002#, Sungang Xi Road, Shenzhen, 518035, People’s Republic of China

    Xiaobin Wang, Yongtian Lu & Huanji Sun

  4. Department of Neurosurgery, Shenzhen The Second People’s Hospital, 3002#, Sungang Xi Road, Shenzhen, 518035, People’s Republic of China

    Songfeng Gong

  5. Department of Neurosurgery, The First Affiliated Hospital of Shenzhen University, 3002#, Sungang Xi Road, Shenzhen, 518035, People’s Republic of China

    Songfeng Gong

  6. Department of ENT, The First Affiliated Hospital of Nanhua University, Hengyang, People’s Republic of China

    Xinggu Luo

Authors
  1. Xiaobin Wang
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  2. Songfeng Gong
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  3. Yongtian Lu
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  4. Xinliang Pan
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  5. Xinggu Luo
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  6. Huanji Sun
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Corresponding authors

Correspondence to Songfeng Gong or Yongtian Lu.

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Xiaobin Wang and Songfeng Gong are co-first authors.

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Wang, X., Gong, S., Lu, Y. et al. Endoscopy-Assisted Transoral Resection of Parapharyngeal Space Tumors: A Retrospective Analysis. Cell Biochem Biophys 71, 1157–1163 (2015). https://doi.org/10.1007/s12013-014-0323-8

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  • DOI: https://doi.org/10.1007/s12013-014-0323-8

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