Abstract
Phytochemical investigation of the 50% ethanol eluate fraction of macroporous resin for the flower of Datura metel L. led to the isolation of a new compound named yangjinhualine A (1) and five known megastigmane sesquiterpenes through repeated silica gel and ODS column chromatography and semipreparative HPLC. The structures of these compounds were determined by spectroscopic methods, including 2D-NMR, ESI-MS, and HR-ESI-MS spectrometry as well as by comparison with published data. Five known megastigmane sesquiterpenes were also isolated from D. metel L. for the first time.
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Dwivedi, A. K., Das, G. P. K., Srivastava, K., Chandra, H., and Khanna, N. M., Synthesis of some β-arylpropionic acid aryl esters and related compounds as potential antifibrinolytic agents. India J. Pharm. Scien., 53, 166–169 (1991).
Jiang, H. X., Li, Y., Pan, J., and Gao, K., Terpenoids from Eupatorium fortunei TURCZ. Helv. Chim. Acta, 89, 558–566 (2006).
Otsuka H., Yao M., Kamada K., and Takeda Y., Alangionosides G-M: Glycosides of megastigmane derivatives from the leaves of Alangium prennifolium. Chem. Pharm. Bull., 43, 754–759 (1995).
Wang, J. S., Shen, Y. M., He, H. P., Kang, W. Y., and Hao, X. J., Norsesquiterpenoid and sesquiterpenoid glycosides from Evodia austrosinensis. Planta Med., 71, 96–98 (2005).
Wang, Q. H., Xiao, H. B., Yang, B. Y., Yao, F. Y., and Kuang, H. X., Studies on pharmacological actions of the effective parts for psoriasis in Flos Daturae (I), Chinese Journal of Experimental Traditional Medical Formulae, 14, 48–51 (2008).
Yang, B. Y., Wang, Q. H., Xia, Y. G., Feng, W. S., and Kuang, H. X., Withanolide compounds from the flower of Datura metel L., Helv. Chim. Acta, 90, 1522–1528 (2007).
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Kuang, Hx., Yang, By., Xia, Yg. et al. Chemical constituents from the flower of Datura metel L.. Arch. Pharm. Res. 31, 1094–1097 (2008). https://doi.org/10.1007/s12272-001-1274-6
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DOI: https://doi.org/10.1007/s12272-001-1274-6