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Prevalence of Vitamin D Deficiency in a Pediatric Hospital of Eastern India

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Abstract

Vitamin D deficiency is highly prevalent in Indian children of northern, western and southern states. Serum 25 hydroxy cholecalferol (ng/ml) was analyzed in 310 children and adolescents of pediatric hospital of Kolkata, India. Serum calcium (mg/dl), phosphorous (mg/dl) and alkaline phosphatase (IU/L) data was obtained. Median 25(OH)D was 19 ng/ml. 19.2 % of population had serum 25(OH)D < 10 ng/ml (severe deficiency), 52.9 % had <20 ng/ml (deficiency), 24.5 % had 20–29 ng/ml (insufficiency) and 22.6 % had >30 ng/ml (optimum). Deficiency was highest in adolescents (86.1 %), followed by school children (61.0 %), lowest in pre-school children (41.6 %). 25(OH)D concentrations was lowest in winters (P = 0.002) and spring (P = 0.03) compared to summer. There was no correlation with calcium (P = 0.99), phosphorous (P = 0.23) and ALP (P = 0.63). There is high prevalence of vitamin D deficiency in children and adolescents of eastern India. Prevalence was lower in younger subjects. 25(OH)D did not correlate with bone mineral markers.

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Authors and Affiliations

  1. Department of Biochemistry, Institute of Child Health, 11, Dr. Biresh Guha Street, Kolkata, 700029, West Bengal, India

    Surupa Basu

  2. Department of Pediatric Medicine, Institute of Child Health, Kolkata, India

    Ruchi Gupta, Monjori Mitra & Apurba Ghosh

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  1. Surupa Basu
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  2. Ruchi Gupta
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Correspondence to Surupa Basu.

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Basu, S., Gupta, R., Mitra, M. et al. Prevalence of Vitamin D Deficiency in a Pediatric Hospital of Eastern India. Ind J Clin Biochem 30, 167–173 (2015). https://doi.org/10.1007/s12291-014-0428-2

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  • DOI: https://doi.org/10.1007/s12291-014-0428-2

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