Skip to main content

Advertisement

SpringerLink
Log in

Guidance Document: Management Priorities in Salicylate Toxicity

  • Position Statement
  • Published:
Journal of Medical Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Done AK (1960) Salicylate intoxication. Significance of measurements of salicylate in blood in cases of acute ingestion. Pediatrics 26:800–807

    CAS  PubMed  Google Scholar 

  2. Dugandzic RM, Tierney MG, Dickinson GE, Dolan MC, McKnight DR (1989) Evaluation of the validity of the Done nomogram in the management of acute salicylate intoxication. Ann Emerg Med 18(11):1186–1190

    Article  CAS  PubMed  Google Scholar 

  3. Alvan G, Bergman U, Gustafsson LL (1981) High unbound fraction of salicylate in plasma during intoxication. Br J Clin Pharmacol 11:625

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  4. Hill JB (1971) Experimental salicylate poisoning: observations on the effects of altering blood pH on tissue and plasma salicylate concentrations. Pediatrics 47:658–665

    CAS  PubMed  Google Scholar 

  5. Stolbach AI, Hoffman RS, Nelson LS (2008) Mechanical ventilation was associated with acidemia in a case series of salicylate-poisoned patients. Acad Emerg Med 15(9):866–869

    Article  PubMed  Google Scholar 

  6. Adelman HM, Wallach PM, Flannery MT (1991) Inability to interpret toxic salicylate levels in patients taking aspirin and diflunisal. J Rheumatol 18(4):522–523

    CAS  PubMed  Google Scholar 

  7. Jacob J, Lavonas EJ (2011) Falsely normal anion gap in severe salicylate poisoning caused by laboratory interference. Ann Emerg Med 58(3):280–281

    Article  PubMed  Google Scholar 

  8. Bradberry SM, Vale JA (1995) Multiple-dose activated charcoal: a review of relevant clinical studies. J Toxicol Clin Toxicol 33:407

    Article  CAS  PubMed  Google Scholar 

  9. Juurlink DN, McGuigan MA (2000) Gastrointestinal decontamination for enteric-coated aspirin overdose: what you do depends on who you ask. J Toxicol Clin Toxicol 38:465

    Article  CAS  PubMed  Google Scholar 

  10. Proudfoot AT, Krenzelok EP, Vale JA (2004) Position paper on urinary alkalinization. J Toxicol Clin Toxicol 42:1

    Article  CAS  PubMed  Google Scholar 

  11. Fertel BS, Nelson LS, Goldfarb DS (2009) The underutilization of hemodialysis in patients with salicylate poisoning. Kidney Int 75(12):1349–1353

    Article  PubMed  Google Scholar 

  12. American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists (1999) Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. J Toxicol Clin Toxicol 37:731

    Article  Google Scholar 

  13. American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists (2005) Position paper: single-dose activated charcoal. Clin Toxicol 43:61

    Google Scholar 

Download references

Author information

Authors and Affiliations

    Consortia

    American College of Medical Toxicology

    Additional information

    Disclaimer

    While individual practitioners may differ, this is the position of the college at the time written, after a review of the issue and pertinent literature. This document identifies critical management priorities for the salicylate-poisoned patient. It is not intended as a clinical guideline or substitute for clinical consultation with a medical toxicologist and a nephrologist.

    Rights and permissions

    Reprints and permissions

    About this article

    Check for updates. Verify currency and authenticity via CrossMark

    Cite this article

    American College of Medical Toxicology. Guidance Document: Management Priorities in Salicylate Toxicity. J. Med. Toxicol. 11, 149–152 (2015). https://doi.org/10.1007/s13181-013-0362-3

    Download citation

    • Published:

    • Issue Date:

    • DOI: https://doi.org/10.1007/s13181-013-0362-3

    Keywords

    Search

    Navigation