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Significant Genetic Linkage of MDR1 Polymorphisms at Positions 3435 and 2677: Functional Relevance to Pharmacokinetics of Digoxin

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Authors and Affiliations

  1. Department of Hospital Pharmacy, School of Medicine, Kobe University, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan

    Masanori Horinouchi, Toshiyuki Sakaeda, Tsutomu Nakamura & Katsuhiko Okumura

  2. Division of Diabetes, Digestive, and Kidney Diseases, Department of Clinical Molecular Medicine, School of Medicine, Kobe University, Kobe, 650-0017, Japan

    Yoshinori Morita, Takao Tamura, Nobuo Aoyama & Masato Kasuga

  3. Department of Endoscopy, School of Medicine, Kobe University, Kobe, 650-0017, Japan

    Nobuo Aoyama

Authors
  1. Masanori Horinouchi
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  2. Toshiyuki Sakaeda
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  3. Tsutomu Nakamura
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  4. Yoshinori Morita
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  5. Takao Tamura
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  6. Nobuo Aoyama
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  7. Masato Kasuga
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  8. Katsuhiko Okumura
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Correspondence to Katsuhiko Okumura.

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Horinouchi, M., Sakaeda, T., Nakamura, T. et al. Significant Genetic Linkage of MDR1 Polymorphisms at Positions 3435 and 2677: Functional Relevance to Pharmacokinetics of Digoxin. Pharm Res 19, 1581–1585 (2002). https://doi.org/10.1023/A:1020433422259

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  • DOI: https://doi.org/10.1023/A:1020433422259

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