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Mucins and Blastocyst Attachment

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References

  1. Noyes RW, Dickmann Z, Doyle LL, Gates AH. Ovum transfers, synchronous and asynchronous, on the study of implantation. In: Enders AC, ed. Delayed Implantation Chicago. IL: University of Chicago Press, 1963:197-211.

    Google Scholar 

  2. Lessey BA. The role of the endometrium during embryo implantation. Hum Reprod 2000;15(Suppl 6):39-50.

    Google Scholar 

  3. Wegner CC, Carson DD. Cell adhesion process in embryo implantation. Oxford Rev Reprod Biol 1994;16:87-135.

    Google Scholar 

  4. Salamonsen LA. Role of protesses in implantation. Rev Reprod 1999;4:11-22.

    Google Scholar 

  5. Lagow E, DeSouza MM, Carson DD. Mammalian reproductive tract mucins. Hum Reprod Update 1999;5(4):280-292.

    Google Scholar 

  6. Gendler SJ, Spicer AP. Epithelial mucin genes. Ann Rev Physiol 1995;57:607-634.

    Google Scholar 

  7. Spicer AP, Parry G, Patton S, Gendler SJ. Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of mini-satellite-like polymorphism. J Biol Chem 1991;266(23):15099-15109.

    Google Scholar 

  8. Kuan SF, Byrd JC, Basbaum C, Kim YS. Inhibition of mucin glycosylation by aryl-N-acetyl-alpha-galactosaminides in human colon cancer cells. J Biol Chem 1989;264(32):19271-19277.

    Google Scholar 

  9. Abdullah KM, Udoh EA, Shewen PE, Mellors A. A neutral glycoprotease of Pasteurella haemolytica Al specifically cleaves O-sialoglycoproteins. Infect Immun 1992;60(1):56-62.

    Google Scholar 

  10. Yang H, Wang S, Liu Z, Wu MH, McAlpine B, Ansel J, Armstrong C, Wu, B. Isolation and characterization of mouse MUC18 cDNA gene, and correlation of MUC18 expression in mouse melanoma cell lines with metastatic ability. Gene 2001;265(1-2):133-145.

    Google Scholar 

  11. Williams SJ, Munster DJ, Quin RJ, Gotley DC, McGuckin MA. The MUC3 gene encodes a transmembrane mucin and is alternatively spliced. Biochem Biophys Res Commun 1999;261(1):83-89.

    Google Scholar 

  12. Moniaux N, Nollet S, Porchet N, Degand P, Lame A, Aubert JP. Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin. Biochem J 1999;338 (Pt 2):325-333.

    Google Scholar 

  13. Williams SJ, McGuckin MA, Gotley DC, Eyre HJ, Sutherland GR, Antalis TM. Two novel mucin genes down-regulated in colorectal cancer identified by differential display. Cancer Res 1999;59(16):4083-4089.

    Google Scholar 

  14. Williams SJ, Wreschner DH, Tran M, Eyre HJ, Sutherland GR, McGuckin MA. Muc13, a novel human cell surface mucin expressed by epithelial and hemopoietic cells. J Biol Chem 2001;276(21):18327-18336.

    Google Scholar 

  15. Yin BW, Lloyd KO. Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16. J Biol Chem 2001;276(29):27371-27375.

    Google Scholar 

  16. Thingstad T, Vos HL, Hilkens J. Biosynthesis and shedding of epiglycanin: a mucin-type glycoprotein of the mouse TA3Ha mammary carcinoma cell. Biochem J 2001;353(Pt 1):33-40.

    Google Scholar 

  17. Pimental RA, Julian J, Gendler SJ, Carson DD. Synthesis and intracellular trafficking of Muc-1 and mucins by polarized mouse uterine epithelial cells. J Biol Chem 1996;271(45):28128-28137.

    Google Scholar 

  18. Boshell M, Lalani EN, Pemberton L, Burchell J, Gendler S, Taylor-Papadimitriou J. The product of the human MUC1 gene when secreted by mouse cells transfected with the full-length cDNA lacks the cytoplasmic tail. Biochem Biophys Res Commun 1992;185(1):1-8.

    Google Scholar 

  19. Smorodinsky N, Weiss M, Hartmann ML, Baruch A, Harness E, Yaakobovitz M, Keydar I, Wreschner DH. Detection of a secreted MUC1/SEC protein by MUC1 isoform specific monoclonal antibodies. Biochem Biophys Res Commun 1996;228(1):115-121.

    Google Scholar 

  20. Zrihan-Licht S, Vos HL, Baruch A, Elroy-Stein O, Sagiv D, Keydar I, Hilkens J, Wreschner, DH. Characterization and molecular cloning of a novel MUC1 protein, devoid of tandem repeats, expressed in human breast cancer tissue. Eur J Biochem 1994;224(2):787-795.

    Google Scholar 

  21. Kovarik A, Lu PJ, Peat N, Morris J, Taylor-Papadimitriou J. Two GC boxes (Spl sites) are involved in regulation of the activity of the epithelium-specific MUC1 promoter. J Biol Chem 1996;271(30):18140-18147.

    Google Scholar 

  22. Gaemers IC, Vos HL, Volders HH, van der Valk SW, Hilkens J. A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells. J Biol Chem 2001;276(9):6191-6199.

    Google Scholar 

  23. Lagow EL, Carson DD. Synergistic stimulation of MUC1 expression in normal breast epithelia and breast cancer cells by interferon-gamma and tumor necrosis factor-alpha. Mol Endocrinol 2001; (Submitted).

  24. Abe M, Kufe D. Characterization of cis-acting elements regulating transcription of the human DF3 breast carcinoma-associated antigen (MUCl) gene. Proc Natl Acad Sci USA 1993;90(1):282-286.

    Google Scholar 

  25. Price-Schiavi SA, Perez A, Barco R, Carraway KL. Cloning and characterization of the 5′ flanking region of the sialomucin complex/rat Muc4 gene: promoter activity in cultured cells. Biochem J 2000;349(Pt 2):641-649.

    Google Scholar 

  26. Perrais M, Pigny P, Ducourouble MP, Petitprez D, Porchet N, Aubert JP, Van Seuningen I. Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinfiammatory cytokines for its regulation in pancreatic cancer cells. J Biol Chem 2001;276(33):30923-30933.

    Google Scholar 

  27. Idris N, Carraway KL. Regulation of sialomucin complex/Muc4 expression in rat uterine luminal epithelial cells by transforming growth factor-beta: implications for blastocyst implantation. J Cell Physiol 2000;185(2):310-316.

    Google Scholar 

  28. Price-Schiavi SA, Zhu X, Aquinin R, Carraway KL. Sialomucin complex (rat Muc4) is regulated by transforming growth factor beta in mammary gland by a novel post-translational mechanism. J Biol Chem 2000;275(23):17800-17807.

    Google Scholar 

  29. McNeer RR, Carraway CA, Fregien NL, Carraway KL. Characterization of the expression and steroid hormone control of sialomucin complex in the rat uterus: implications for uterine receptivity. J Cell Physiol 1998;176(1):110-119.

    Google Scholar 

  30. Surveyor GA, Gendler SJ, Pemberton L, Das SK, Chakraborty I, Julian J, Pimental RA, Wegner CC, Dey SK, Carson DD. Expression and steroid hormonal control of Muc-1 in the mouse uterus. Endocrinology 1995;136(8):3639-3647.

    Google Scholar 

  31. Hild-Petito S, Fazleabas AT, Julian J, Carson DD. Mucin (Muc-1) expression is differentially regulated in uterine luminal and glandular epithelia of the baboon (Papio anubis). Biol Reprod 1996;54(5):939-947.

    Google Scholar 

  32. Bowen JA, Bazer FW, Burghardt RC. Spatial and temporal analyses of integrin and Muc-1 expression in porcine uterine epithelium and trophectoderm in vivo. Biol Reprod 1996;55(5):1098-1106.

    Google Scholar 

  33. Zhou X, DeSouza MM, Julian J, Gendler SJ, Carson DD. Estrogen receptor does not directly regulate the murine Muc-1 promoter. Mol Cell Endocrinol 1998;143(1-2):65-78.

    Google Scholar 

  34. Meseguer M, Aplin JD, Caballero-Campo P, O'Connor JE, Martin JC, Remohi J, Pellicer A, Simon C. Human endometrial mucin MUC1 is up-regulated by progesterone and down-regulated in vitro by the human blastocyst. Biol Reprod 2001;64(2):590-601.

    Google Scholar 

  35. Zaretsky JZ, Sarid R, Aylon Y, Mittelman LA, Wreschner DH, Keydar I. Analysis of the promoter of the MUC1 gene overexpressed in breast cancer. FEBS Lett 1999;461(3):189-195.

    Google Scholar 

  36. Hilkens J, Buijs F. Biosynthesis of MAM-6, an epithelial sialomucin. Evidence for involvement of a rare proteolytic cleavage step in the endoplasmic reticulum. J Biol Chem 1988;263(9):4215-4222.

    Google Scholar 

  37. Linsley PS, Kallestad JC, Horn D. Biosynthesis of high molecular weight breast carcinoma associated mucin glycoproteins. J Biol Chem 1988;263(17):8390-8397.

    Google Scholar 

  38. Pimental RA, Julian J, Gendler SJ, Carson DD. Synthesis and intracellular trafficking of Muc-1 and mucins by polarized mouse uterine epithelial cells. J Biol Chem 1996;271(45):2812828137.

    Google Scholar 

  39. Litvinov SV, Hilkens J. The epithelial sialomucin, episialin, is sialylated during recycling. J Biol Chem 1993;268(28):21364-21371.

    Google Scholar 

  40. Ligtenberg MJ, Kruijshaar L, Buijs F, van Meijer M, Litvinov SV, Hilkens J. Cell-associated episialin is a complex containing two proteins derived from a common precursor. J Biol Chem 1992;267(9):6171-6177.

    Google Scholar 

  41. Sheng ZQ, Hull SR, Carraway KL. Biosynthesis of the cell surface sialomucin complex of ascites 13762 rat mammary adenocarcinoma cells from a high molecular weight precursor. J Biol Chem 1990;265(15):8505-8510.

    Google Scholar 

  42. Bork P, Patthy L. The SEA module: a new extracellular domain associated with O-glycosylation. Protein Sci 1995;4(7):1421-1425.

    Google Scholar 

  43. Fiedler F. Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin. Eur J Biochem 1987;163(2):303-312.

    Google Scholar 

  44. Parry S, Silverman HS, McDermott K, Willis A, Hollingsworth MA, Harris A. Identification of MUC1 proteolytic cleavage sites in vivo. Biochem Biophys Res Commun 2001;283(3):715-720.

    Google Scholar 

  45. Jentoft N. Why are proteins O-glycosyaated? Trends Biochem Sci 1990;15(8):291-294.

    Google Scholar 

  46. Altschuler Y, Kinlough CL, Poland PA, Bruns JB, Apodaca G, Weisz OA, Hugrey RP. Clathrin-mediated endocytosis of MUC1 is modulated by its glycosylation state. Mol Biol Cell 2000;11(3):819-831.

    Google Scholar 

  47. Mullberg J, Althoff K, Jostock T, Rose-John S. The importance of shedding of membrane proteins for cytokine biology. Eur Cytokine Netw 2000;11(1):27-38.

    Google Scholar 

  48. Schlondorff J, Becherer JD, Blobel CP. Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE). Biochem J 2000;347(Pt 1):131-138.

    Google Scholar 

  49. Patton S, Gendler SJ, Spicer AP. The epithelial mucin, MUC1, of milk, mammary gland and other tissues. Biochim Biophys Acta 1995;1241(3):407-423.

    Google Scholar 

  50. Izumi Y, Hirata M, Hasuwa H, Iwamoto R, Umata T, Miyado K, Tamai Y, Kurisaki T, Sehara-Fujisan A, Ohno S, Mekuda E. A metal loprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Embo J 1998;17(24):7260-7272.

    Google Scholar 

  51. Roghani M, Becherer JD, Moss ML, Atherton RE, Erdjument-Bromage H, Arribas J, Blackburn RK, Weskamp G, Tempst P, Blobel CP. Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. J Biol Chem 1999;274(6):3531-3540.

    Google Scholar 

  52. Olson GE, Winfrey VP, Matrisian PE, NagDas SK, Hoffman LH. Blastocyst-dependent upregulation of metal loproteinase/disintegrin MDC9 expression in rabbit endometrium. Cell Tissue Res 1998;293(3):489-498.

    Google Scholar 

  53. Hoffman LH, Olson GE, Carson DD, Chilton BS. Progesterone and implanting blastocysts regulate Mucl expression in rabbit uterine epithelium. Endocrinology 1998;139(1):266-271.

    Google Scholar 

  54. Hey NA, Li TC, Devine PL, Graham RA, Saravelos H, Aplin JD. MUC1 in secretory phase endometrium: expression in precisely dated biopsies and flushings from normal and recurrent miscarriage patients. Hum Reprod 1995;10(10):2655-2662.

    Google Scholar 

  55. Aplin JD, Hey NA, Li TC. MUC1 as a cell surface and secretory component of endometrial epithelium: reduced levels in recurrent miscarriage. Am J Reprod Immunol 1996;35(3):261-266.

    Google Scholar 

  56. Scharfman A, Lamblin G, Roussel P. Interactions between human respiratory mucins and pathogens. Biochem Soc Trans 1995;23(4):836-839.

    Google Scholar 

  57. DeSouza MM, Surveyor GA, Price RE, Julian J, Kardon R, Zhou X, Gendler SJ, Hilkens J, Carson DD. MUC1/episialin: a critical barrier in the female reproductive tract. J Reprod Immunol 1999;45(2):127-158.

    Google Scholar 

  58. Kardon R, Price RE, Julian J, Lagow E, Tseng SC, Gendler SJ, Carson DD. Bacterial conjunctivitis in Mucl null mice. Invest Ophthalmol Vis Sci 1999;40(7):1328-1335.

    Google Scholar 

  59. Croy BA, Ashkar AA, Foster RA, DiSanto JP, Magram J, Carson D, Gendler SJ, Grusley MJ, Wagner H, Muller W, Guimond MJ. Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy. J Reprod Immunol 1997;35(2):111-133.

    Google Scholar 

  60. Arcasoy SM, Laroche J, Gondor M, Watkins SC, Henderson RA, Hughey R, Finn OS, Pilewski JM. MUC1 and other sialoglyco-conjugates inhibit adenovirus-mediated gene transfer to epithelial cells. Am J Respir Cell Mol Biol 1997;17(4):422-435.

    Google Scholar 

  61. Lillehoj EP, Hyun SW, Kim BT, Zhang XG, Lee DI, Rowland S, Kim KC. Mucl mucins on the cell surface are adhesion sites for Pseudomonas aeruginosa. Am J Physiol Lung Cell Mol Physiol 2001;280(1):L181-187.

    Google Scholar 

  62. Venegas MF, Navas EL, Gaffney RA, Duncan JL, Anderson BE, Schaeffer AJ. Binding of type 1-piliated Escherichia coli to vaginal mucus. Infect Immun 1995;63(2):416-422.

    Google Scholar 

  63. Hey NA, Aplin JD. Sialyl-Lewis X and Sialyl-Lewis A. are associated with MUC1 in human endometrium. Glycoconj J 1996;13(5):769-779.

    Google Scholar 

  64. DeLoia JA, Krasnow JS, Brekosky J, Babaknia A, Julian J, Carson DD. Regional specialization of the cell membrane-associated, polymorphic mucin (MUC1) in human uterine epithelia. Hum Reprod 1998;13(10):2902-2909.

    Google Scholar 

  65. Aplin JD, Hey NA, Graham RA. Human endometrial MUC1 carries keratan sulfate: characteristic glycoforms in the luminal epithelium at receptivity. Glycobiology 1998;8(3):269-276.

    Google Scholar 

  66. Valdizan MC, Julian J, Carson DD. WGA-binding, mucin glycoproteins protect the apical cell surface of mouse uterine epithelial cells. J Cell Physiol 1992;151(3):451-465.

    Google Scholar 

  67. Kondo K, Kohno N, Yokoyama A, Hiwada K. Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines. Cancer Res 1998;58(9):2014-2019.

    Google Scholar 

  68. Wesseling J, van der Valk SW, Hilkens J. A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1. Mol Biol Cell 1996;7(4):565-577.

    Google Scholar 

  69. Komatsu M, Carraway CA, Fregien NL, Carraway KL. Reversible disruption of cell-matrix and cell-cell interactions by over-expression of sialomucin complex. J Biol Chem 1997;272(52):33245-33254.

    Google Scholar 

  70. Kemperman H, Wijnands Y, Wesseling J, Niessen CM, Sonnenberg A, Roos E. The mucin epiglycanin on TA3/Ha carcinoma cells prevents alpha 6 beta 4-mediated adhesion to laminin and kalinin and E-cadherin-mediated cell-cell interaction. J Cell Biol 1994;127(6 Pt 2):2071-2080.

    Google Scholar 

  71. Codington JF, Frim DM. Cell-surface macromolecular and morphological changes related to allotransplantability in the TA3 tumor. Biomembranes 1983;11:207-258.

    Google Scholar 

  72. Becker JW, Erickson HP, Hoffman S, Cunningham BA, Edelman GM. Topology of cell adhesion molecules. Proc Natl Acad Sci USA 1989;86(3):1088-1092.

    Google Scholar 

  73. Murphy CR, Hosie MJ, Thompson MB. The plasma membrane transformation facilitates pregnancy in both reptiles and mammals. Comp Biochem Physiol A Mol Integr Physiol 2000;127(4):433-439.

    Google Scholar 

  74. Tsuboi S, Fukuda M. Roles of O-linked oligosaccharides in immune responses. Bioessays 2001;23(1):46-53.

    Google Scholar 

  75. Agrawal B, Krantz MJ, Reddish MA, Longenecker BM. Cancerassociated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2. Nat Med 1998;4(1):43-49.

    Google Scholar 

  76. Fung PY, Longenecker BM. Specific immunosuppressive activity of epiglycanin, a mucin-like glycoprotein secreted by a murine mammary adenocarcinoma (TA3-HA). Cancer Res 1991;51(4):1170-1176.

    Google Scholar 

  77. Gimmin CD, Morrison BW, Mainprice BA, Gribben JG, Boussiotis VA, Freeman GJ, et al. Breast Cancer-associated antigen, DF3/MUC1, induces apoptosis of activated human T cells. Nat Med 1996;2:1367-1370.

    Google Scholar 

  78. van de Wiel-van Kemenade E, Ligtenberg MJ, de Boer AJ, Buijs F, Vos HL, Melief CJ, Hilkens J, Fidgor CG. Episialin (MUCl) inhibits cytotoxic lymphocyte-target cell interaction. J Immunol 1993;151(2):767-776.

    Google Scholar 

  79. Komatsu M, Yee L, Carraway KL. Overexpression of sialomucin complex, a rat homologue of MUC4, inhibits tumor killing by lymphokine-activated killer cells. Cancer Res 1999;59(9):2229-2236.

    Google Scholar 

  80. Carraway KL, III, Rossi EA, Komatsu M, Price-Schiavi SA, Huang D, Guy PM, Carvajal ME, Fregien N, Carraway CA, Carraway KL. An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling. J Biol Chem 1999;274(9):5263-5266.

    Google Scholar 

  81. Schroeder JA, Thompson MC, Gardner MM, Gendler SJ. Transgenic MUC 1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J Biol Chem 2001;276(16):1305713064.

    Google Scholar 

  82. Meerzaman D, Shapiro PS, Kim KC. Involvement of the MAP kinase ERK2 in MUC1 mucin signaling. Am J Physiol Lung Cell Mol Physiol 2001;281(1):L86-91.

    Google Scholar 

  83. Li Y, Kuwahara H, Ren J, Wen G, Kufe D. The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinomaassociated antigen with GSK3 beta and beta-catenin. J Biol Chem 2001;276(9):6061-6064.

    Google Scholar 

  84. Li Y, Bharti A, Chen D, Gong J, Kufe D. Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin. Mol Cell Biol 1998;18(12):7216-7224.

    Google Scholar 

  85. Hey NA, Graham RA, Seif MW, Aplin JD. The polymorphic epithelial mucin MUC1 in human endometrium is regulated with maximal expression in the implantation phase. J Clin Endocrinol Metab 1994;78(2):337-342.

    Google Scholar 

  86. Pandey P, Kharbanda S, Kufe D. Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein. Cancer Res 1995;55(18):4000-4003.

    Google Scholar 

  87. Li Y, Kufe D. The Human DF3/MUC1 carcinoma-associated antigen signals nuclear localization of the catenin pl20(ctn). Biochem Biophys Res Commun 2001;281(2):440-443.

    Google Scholar 

  88. Carson DD, Bagchi I, Dey SK, Enders AC, Fazleabas AT, Lessey BA, Yoshinaga K. Embryo implantation. Dev Biol 2000;223(2):217-237.

    Google Scholar 

  89. Nikas G, Psychoyos A. Uterine pinopodes in peri-implantation human endometrium. Clinical relevance. Ann NY Acad Sci 1997;816:129-142.

    Google Scholar 

  90. Mullins DE, Horst MN, Bazer FW, Roberts RM. Isolation and characterization of a plasma membrane fraction derived from the luminal surface of the pig uterus during the estrous cycle and early pregnancy. Biol Reprod 1980;22(5):1181-1192.

    Google Scholar 

  91. Carson DD, Tang JP, Julian J, Glasser SR. Vectorial secretion of proteoglycans by polarized rat uterine epithelial cells. J Cell Biol 1988;107(6 Pt 1):2425-2435.

    Google Scholar 

  92. Mani SK, Carson DD, Glasser SR. Steroid hormones differentially modulate glycoconjugate synthesis and vectorial secretion by polarized uterine epithelial cells in vitro. Endocrinology 1992;130(1):240-248.

    Google Scholar 

  93. Julian J, Carson DD, Glasser SR. Polarized rat uterine epithelium in vitro: responses to estrogen in defined medium. Endocrinology 1992;130(1):68-78.

    Google Scholar 

  94. Dutt A, Carson DD. Lactosaminoglycan assembly, cell surface expression, and release by mouse uterine epithelial cells. J Biol Chem 1990;265(1):430-438.

    Google Scholar 

  95. DeSouza MM, Mani SK, Julian J, Carson DD. Reduction of mucin-1 expression during the receptive phase in the rat uterus. Biol Reprod 1998;58(6):1503-1507.

    Google Scholar 

  96. Vinijsanun A, Martin L. Effects of progesterone antagonists RU486 and ZK98734 on embryo transport, development and implantation in laboratory mice. Reprod Fertil Dev 1990;2(6):713-727.

    Google Scholar 

  97. Milligan SR, Finn CA. Minimal progesterone support required for the maintenance of pregnancy in mice. Hum Reprod 1997;12(3):602-607.

    Google Scholar 

  98. Chervenak JL, Illsley NP. Episialin acts as an antiadhesive factor in an in vitro model of human endometrial-blastocyst attachment. Biol Reprod 2000;63(1):294-300.

    Google Scholar 

  99. Johnson GA, Bazer FW, Jaeger LA, Ka H, Garlow JE, Pfarrer C, Spencer TE, Burghadt CC. Muc-1, integrin, and osteopontin expression during the implantation cascade in sheep. Biol Reprod 2001;65(3):820-828.

    Google Scholar 

  100. Jones CJ, Ortiz ME, Croxatto HB, Manzur A, Slevin G, Aplin JD. Muc1 and glycan expression in the oviduct and endometrium of a New World monkey, Cebus apella. Biol Reprod 2001;64(5):1535-1544.

    Google Scholar 

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  1. Department of Biological Sciences, University of Delaware, Newark, DE, 19716, USA

    Amantha Thathiah & Daniel D. Carson

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Thathiah, A., Carson, D.D. Mucins and Blastocyst Attachment. Rev Endocr Metab Disord 3, 87–96 (2002). https://doi.org/10.1023/A:1015446626671

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