Abstract
We did a follow-up study based upon a regional prescription register in Denmark. We identified all 435 women who in the period 1991–1996 had redeemed a prescription for CNS drugs during pregnancy. Among the rest of the pregnant women we randomly selected 1304 women who also had given birth to a child in the same region and period. We looked up the local health nurses Boel test results which were available for about 80%. Any abnormal test result was seen much more frequently among exposed (16%) than for not exposed (4%). The study has several limitations but raises concern that should be addressed in other and better designed studies.
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Mortensen, J., Olsen, J., Larsen, H. et al. Psychomotor development in children exposed in utero to benzodiazepines, antidepressants, neuroleptics, and anti-epileptics. Eur J Epidemiol 18, 769–771 (2003). https://doi.org/10.1023/A:1025306304635
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DOI: https://doi.org/10.1023/A:1025306304635