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Clinical onset of celiac disease after duodenal switch: a case report

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Abstract

To our knowledge, this is the first reported case of clinical onset of celiac disease (CD) following duodenal switch surgery. A 61-year-old obese woman developed severe diarrhea soon after bariatric surgery (BS), which was unresponsive to standard medical treatment. After the most common diarrhea etiologies in the immediate postoperative period have been excluded, serological tests were performed. Final diagnosis was determined by anti-tissue transglutaminase antibody positivity. In light of this case report, we propose that CD should be ruled out in any patient presenting with typical or atypical symptoms after BS, regardless of the latency of onset.

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References

  1. Ukkola A, Mäki M, Kurppa K, Collin P, Huhtala H, Kekkonen L et al. Changes in body mass index on a gluten-free diet in coeliac disease: a nationwide study. EJIM 2012; 23: 384–388.

    Google Scholar 

  2. Rampertab SD, Pooran N, Brar P, Singh P, Green PHR . Trends in the presentation of celiac disease. Am J Med 2006; 119: 355.e9–355.e14.

    Article  Google Scholar 

  3. Green PH, Jabri B . Coeliac disease. Lancet 2003; 362: 383–391.

    Article  CAS  Google Scholar 

  4. González-Molero I, Morcillo S, Valdés S, Pérez-Valero V, Botas P, Delgado E et al. Vitamin D deficiency in Spain: a population-based cohort study. EJCN 2011; 65: 321–328.

    PubMed  Google Scholar 

  5. Deepu D, Hardigan P, Bray N, Penzell D, Savu C . The incidence of vitamin D deficiency in the obese: a retrospective chart review. J Community Hosp Intern Med Perspect 2015; 5: 26069.

    Article  Google Scholar 

  6. Maple JT, Pearson RK, Murray JA, Kelly DG, Lara LF, Fan AC . Silent celiac disease activated by pancreaticoduodenectomy. Dig Dis Sci 2007; 52: 2141–2144.

    Article  Google Scholar 

  7. Nenna R, Mosca A, Mennini M, Edo Papa R, Petrarca L, Mercurio R et al. Coeliac disease screening among a large cohort of overweight/obese children. JPGN 2015; 60: 405–407.

    CAS  PubMed  Google Scholar 

  8. Mechanick JI, Youdim A, Jones DB, Garvey WT, Hurley DL, McMahon M et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient—2013 update: cosponsored by American Association of Clinical Endocrinologists, the Obesity Society, and American Society for Metabolic & Bariatric Surgery. Endocr Pract 2013; 19: 337–372.

    Article  Google Scholar 

  9. De’Angelis N, Carra MC, Vicenzi F . Gluten-free diet in obese patients with celiac disease: an enemy of the bariatric surgeon? Obes Surg 2012; 22: 995–996.

    Article  Google Scholar 

  10. Kabbani TA, Goldberg A, Kelly CP, Pallav K, Peer A, Hansen J et al. Body mass index and the risk of obesity in coeliac disease treated with the gluten-free diet. Aliment Pharmacol Ther 2012; 35: 723–729.

    Article  CAS  Google Scholar 

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Correspondence to A J Amor.

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Pané, A., Orois, A., Careaga, M. et al. Clinical onset of celiac disease after duodenal switch: a case report. Eur J Clin Nutr 70, 1078–1079 (2016). https://doi.org/10.1038/ejcn.2016.65

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