Notch is essential for T lineage cell differentiation. Three new papers look at when Notch signaling is required and how it affects different cell types.
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von Boehmer, H. Notch in lymphopoiesis and T cell polarization. Nat Immunol 6, 641–642 (2005). https://doi.org/10.1038/ni0705-641
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DOI: https://doi.org/10.1038/ni0705-641