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Erythrocyte Substitute for Perfusion of Brain

Abstract

In a simulated blood plasma ‘FX-80’, a liquid fluorocarbon with a high solubility for oxygen, maintains the electrical activity of a preparation of isolated rat brain. This is as effective as a suspension of erythrocytes in the same simulated blood plasma.

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References

  1. Burk, D., Hearon, J., Caroline, L., and Schade, A. L., J. Biol. Chem., 165, 723 (1946).

    CAS  PubMed  Google Scholar 

  2. Michaelis, L., Arch. Biochem., 17, 201 (1948).

    CAS  PubMed  Google Scholar 

  3. Drabkin, D. L., Science, 101, 445 (1945).

    Article  ADS  CAS  Google Scholar 

  4. Clark, L. C., and Gollan, F., Science, 152, 1755 (1966).

    Article  ADS  CAS  Google Scholar 

  5. Gollan, F., and Clark, L. C., The Physiologist, 9, 191 (1966).

    Google Scholar 

  6. Andjus, R., Suhara, K., and Sloviter, H. A., J. Appl. Physiol., 22, 1033 (1967).

    Article  CAS  Google Scholar 

  7. Horn, H. D., and Bruns, F. H., Biochim. Biophys. Acta, 21, 378 (1956).

    Article  CAS  Google Scholar 

Download references

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SLOVITER, H., KAMIMOTO, T. Erythrocyte Substitute for Perfusion of Brain. Nature 216, 458–460 (1967). https://doi.org/10.1038/216458a0

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