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A phenylethylamine oxidising defect in migraine

Abstract

FOR some two hundred years, certain foodstuffs have been known to trigger migraine attacks1. In 1967, knowing that cheese is a common dietary trigger to migraine, Hanington2 fed tyramine, which it is known to contain, to affected subjects and by this action was able to initiate headache episodes.

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SANDLER, M., YOUDIM, M. & HANINGTON, E. A phenylethylamine oxidising defect in migraine. Nature 250, 335–337 (1974). https://doi.org/10.1038/250335a0

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