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Hormonal regulation of peptide receptors and target cell responses

Nature volume 280, pages 109–116 (1979)Cite this article

Abstract

Regulation of plasma membrane receptors for peptide hormones by the prevailing ligand concentration often causes altered target cell function. Receptor number is determined by hormone-induced changes in membrane conformation, irreversible ligand binding, and processing of ligand–receptor complexes during hormone action.

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  1. Endocrinology and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, 20205

    K. J. Catt, J. P. Harwood, G. Aguilera & M. L. Dufau

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Catt, K., Harwood, J., Aguilera, G. et al. Hormonal regulation of peptide receptors and target cell responses. Nature 280, 109–116 (1979). https://doi.org/10.1038/280109a0

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