Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Immunology

T cells and tumours

Nature volume 411, pages 1010–1012 (2001)Cite this article

The immune system's response to new tumours is complicated but seems to depend on where and when tumours develop. This will have to be much better understood to enlist a patient's immune defences in fighting cancer.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: T-cell responses to tumours in different circumstances.

References

  1. Shankaran, V. et al. Nature 410, 1107–1111 (2001).

    Article  ADS  CAS  Google Scholar 

  2. Ochsenbein, A. F. et al. Nature 411, 1058–1064 (2001).

    Article  ADS  CAS  Google Scholar 

  3. Travers, P. J., Arklie, J. L., Trowsdale, J., Patillo, R. A. & Bodmer, W. F. Natl Cancer Inst. Monogr. 60, 175–180 (1982).

    CAS  PubMed  Google Scholar 

  4. Marincola, F. M., Jaffee, E. M., Hicklin, D. J. & Ferrone, S. Adv. Immunol. 74, 181–273 (2000).

    Article  CAS  Google Scholar 

  5. Trowsdale, J., Travers, P., Bodmer, W. F. & Patillo, R. A. J. Exp. Med. 152, 11–17 (1980).

    CAS  Google Scholar 

  6. Restifo, N. P. et al. J. Exp. Med. 177, 265–272 (1993).

    Article  CAS  Google Scholar 

  7. Groopman, J. E. Semin. Oncol. 14, 1–6 (1987).

    CAS  PubMed  Google Scholar 

  8. Stutman, O. J. Natl Cancer Inst. 2, 353–358 (1979).

    Google Scholar 

  9. Lauritzsen, G. F., Weiss, S., Dembic, Z. & Bogen, B. Proc. Natl Acad. Sci. USA 91, 5700–5704 (1994).

    Article  ADS  CAS  Google Scholar 

  10. Speiser, D. E. et al. J. Exp. Med. 186, 645–653 (1997).

    Article  CAS  Google Scholar 

  11. Staveley-O'Carroll, K. et al. Proc. Natl Acad. Sci. USA 95, 1178–1183 (1998).

    Article  ADS  CAS  Google Scholar 

  12. Huang, A.Y. et al. Science 264, 961–965 (1994).

    Article  ADS  CAS  Google Scholar 

  13. Toes, R. E. et al. Cancer Res. 56, 3782–3787 (1996).

    CAS  PubMed  Google Scholar 

  14. Fuchs, E. J. & Matzinger, P. Semin. Immunol. 8, 271–280 (1996).

    Article  CAS  Google Scholar 

  15. Adler, A. J. et al. J. Exp. Med. 187, 1555–1564 (1998).

    Article  CAS  Google Scholar 

  16. Miller, J. F. et al. Immunol. Rev. 165, 267–277 (1998).

    Article  CAS  Google Scholar 

  17. Sotomayor, E. et al. Blood (in the press).

Download references

Author information

Authors and Affiliations

  1. Department of Oncology, Medicine, Pathology, Molecular Biology and Genetics, Johns Hopkins University, Baltimore, 21231, Maryland, USA

    Drew Pardoll

Authors
  1. Drew Pardoll
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Drew Pardoll.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pardoll, D. T cells and tumours. Nature 411, 1010–1012 (2001). https://doi.org/10.1038/35082676

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/35082676

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing