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Lung Krüpple-like factor: a quintessential player in T cell quiescence

The molecular events behind T cell quiescence are poorly understood. Evidence is now emerging that the transcription factor LKLF can potentially programme cells to a resting state in a c-Myc–dependent manner.

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Figure 1: Central role of LKLF in T cell quiescence.

Bob Crimi

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Di Santo, J. Lung Krüpple-like factor: a quintessential player in T cell quiescence. Nat Immunol 2, 667–668 (2001). https://doi.org/10.1038/90598

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