Cellular organelles called mitochondria contain their own DNA. The discovery that variation in mitochondrial DNA alters physiology and lifespan in mice has implications for evolutionary biology and the origins of disease. See Letter p.561
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Wallace, D. Mitochondrial DNA in evolution and disease. Nature 535, 498–500 (2016). https://doi.org/10.1038/nature18902
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DOI: https://doi.org/10.1038/nature18902
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