The regulation of T cell survival and apoptosis contributes to the pathogenesis of autoimmune disease. A new study shows that the transcriptional regulator β-arrestin 1 enhances antiapoptotic Bcl-2 in T cells, which can heighten autoimmune disease.
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Frederick, T., Miller, S. Arresting autoimmunity by blocking β-arrestin 1. Nat Immunol 8, 791–792 (2007). https://doi.org/10.1038/ni0807-791
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DOI: https://doi.org/10.1038/ni0807-791
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