Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

A liquid biopsy for cancer immunotherapy

Nature Medicine volume 22, pages 340–341 (2016)Cite this article

Subjects

Human T cells that target tumor-specific mutations are attractive for cancer immunotherapy, but obtaining these T cells is challenging. A new study shows that tumor mutation–specific T cells can be isolated from the peripheral blood of patients with melanoma.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Tapping the blood for cancer immunotherapy.

References

  1. Rosenberg, S.A. & Restifo, N.P. Science 348, 62–68 (2015).

    Article  CAS  Google Scholar 

  2. Schumacher, T.N. & Schreiber, R.D. Science 348, 69–74 (2015).

    Article  CAS  Google Scholar 

  3. van Rooij, N. et al. J. Clin. Oncol. 31, e439–e442 (2013).

    Article  Google Scholar 

  4. Rizvi, N.A. et al. Science 348, 124–128 (2015).

    Article  CAS  Google Scholar 

  5. Gros, A. et al. Nat. Med. 22, 433–438 (2016).

    Article  CAS  Google Scholar 

  6. Gros, A. et al. J. Clin. Invest. 124, 2246–2259 (2014).

    Article  CAS  Google Scholar 

  7. Zanetti, M. J. Immunol. 194, 2049–2056 (2015).

    Article  CAS  Google Scholar 

  8. Linnemann, C. et al. Nat. Med. 21, 81–85 (2015).

    Article  CAS  Google Scholar 

  9. Tran, E. et al. Science 344, 641–645 (2014).

    Article  CAS  Google Scholar 

  10. Haber, D.A. & Velculescu, V.E. Cancer Discov. 4, 650–661 (2014).

    Article  CAS  Google Scholar 

  11. Lohr, J.G. et al. Nat. Biotechnol. 32, 479–484 (2014).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ton N. Schumacher and Wouter Scheper are in the Division of Immunology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.,

    Ton N Schumacher & Wouter Scheper

Authors
  1. Ton N Schumacher
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wouter Scheper
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Ton N Schumacher.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Schumacher, T., Scheper, W. A liquid biopsy for cancer immunotherapy. Nat Med 22, 340–341 (2016). https://doi.org/10.1038/nm.4074

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm.4074

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing