Clinical investigation of enlarged, local lymph nodes after surgery for papillary thyroid carcinoma is problematic. Use of the fine-needle aspiration thyroglobulin assay could help to identify patients whose disease has progressed to lymph-node metastasis.
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Costante, G., Filetti, S. Thyroglobulin in fine-needle aspirates—a clue to metastasis?. Nat Rev Endocrinol 5, 249–250 (2009). https://doi.org/10.1038/nrendo.2009.55
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DOI: https://doi.org/10.1038/nrendo.2009.55
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