Pregnancy is described as the window to a woman's future health. A study by Feig et al. has found an increased risk of diabetes mellitus later in life in women with a history of pre-eclampsia or gestational hypertension, which suggests the need for screening and preventative measures in these women.
Key Points
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Complications occurring during pregnancy increase the risk of metabolic diseases later in life
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Pre-eclampsia and gestational hypertension increase the risk of diabetes mellitus years after delivery
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Women who have had gestational diabetes mellitus, gestational hypertension or pre-eclampsia could benefit from targeted screening and early interventions to decrease their risk of developing diabetes mellitus
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References
Lindheimer, M. D., Taler, S. J., Cunningham, F. G. & American Society of Hypertension. ASH position paper: hypertension in pregnancy. J. Clin. Hypertens. (Greenwich) 11, 214–225 (2009).
Feig, D. S. et al. Preeclampsia as a risk factor for diabetes: a population-based cohort study. PLoS Med. 10, e1001425 (2013).
Berends, A. L. et al. Shared constitutional risks for maternal vascular-related pregnancy complications and future cardiovascular disease. Hypertension 51, 1034–1041 (2008).
Calderon-Margalit, R. et al. Late stillbirths and long-term mortality of mothers. Obstet. Gynecol. 109, 1301–1308 (2007).
Fuh, M. M. et al. Resistance to insulin-mediated glucose uptake and hyperinsulinemia in women who had preeclampsia during pregnancy. Am. J. Hypertens. 8, 768–771 (1995).
Lykke, J. A. et al. Hypertensive pregnancy disorders and subsequent cardiovascular morbidity and type 2 diabetes mellitus in the mother. Hypertension 53, 944–951 (2009).
Magnussen, E. B., Vatten, L. J., Smith, G. D. & Romundstad, P. R. Hypertensive disorders in pregnancy and subsequently measured cardiovascular risk factors. Obstet. Gynecol. 114, 961–970 (2009).
Männistö, T. et al. Elevated blood pressure in pregnancy and subsequent chronic disease risk. Circulation 127, 681–690 (2013).
Smith, G. C., Pell, J. P. & Walsh, D. Pregnancy complications and maternal risk of ischaemic heart disease: a retrospective cohort study of 129,290 births. Lancet 357, 2002–2006 (2001).
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Feghali, M., Miodovnik, M. Hypertension during pregnancy and future diabetes mellitus. Nat Rev Endocrinol 9, 446–447 (2013). https://doi.org/10.1038/nrendo.2013.110
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DOI: https://doi.org/10.1038/nrendo.2013.110