Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Obesity

Bariatric surgery, weight loss and bone

Nature Reviews Endocrinology volume 9, pages 630–632 (2013)Cite this article

Subjects

The unprecedented increase in the prevalence of obesity has been followed by a rapid rise in bariatric surgery. Bone has been linked with fat metabolism. Thus, if weight loss increases the risk of osteoporosis, understanding the effect bariatric surgery has on bone health is vital. Two recent articles contribute to this area of research.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Adams, T. D. et al. Health benefits of gastric bypass surgery after 6 years. JAMA 308, 1122–1131 (2012).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Sjöström, L. Review of the key results from the Swedish Obese Subjects (SOS) trial—a prospective controlled intervention study of bariatric surgery. J. Intern. Med. 273, 219–234 (2013).

    Article  PubMed  Google Scholar 

  3. Sjöström, L. et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N. Engl. J. Med. 357, 741–752 (2007).

    PubMed  Google Scholar 

  4. Nakamura, K. M. et al. Fracture risk following bariatric surgery: a population-based study. Osteoporos. Int. http://dx.doi.org/10.1007/s00198-013-2463-x.

  5. Yu, E. W. et al. Bone loss after bariatric surgery: Discordant results between DXA and QCT bone density. J. Bone Miner. Res. http://dx.doi.org/10.1002/jbmr.2063.

  6. Premaor, M. O. et al. Obesity and fractures in postmenopausal women. J. Bone Miner. Res. 25, 292–297 (2010).

    Article  PubMed  Google Scholar 

  7. Center, J. R., Bliuc, D., Nguyen, T. V. & Eisman, J. A. Risk of subsequent fracture after low-trauma fracture in men and women. JAMA 297, 387–394 (2007).

    Article  CAS  PubMed  Google Scholar 

  8. Lalmohamed, A. et al. Risk of fracture after bariatric surgery in the United Kingdom: population based, retrospective cohort study. BMJ 345, e5085 (2012).

    Article  PubMed  PubMed Central  Google Scholar 

  9. Brzozowska, M. M., Sainsbury, A., Eisman, J. A., Baldock, P. A. & Center, J. R. Bariatric surgery, bone loss, obesity and possible mechanisms. Obes. Rev. 14, 52–67 (2013).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Osteoporosis and Bone Biology Division, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, 2010, NSW, Australia

    Jacqueline R. Center

  2. Department of Endocrinology and Metabolism, Prince of Wales Hospital, Randwick, Sydney, 2031, NSW, Australia

    Chris P. White

Authors
  1. Jacqueline R. Center
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chris P. White
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jacqueline R. Center.

Ethics declarations

Competing interests

J. R. Center has received support and/or honoraria for speaking from Amgen, Merck Sharpe and Dohme, Novartis, Sanofi-Aventis. C. P. White has received support from Amgen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Center, J., White, C. Bariatric surgery, weight loss and bone. Nat Rev Endocrinol 9, 630–632 (2013). https://doi.org/10.1038/nrendo.2013.189

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrendo.2013.189

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing