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Chronic kidney disease

Obesity in children with end-stage renal disease

Nature Reviews Nephrology volume 9, pages 707–708 (2013)Cite this article

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A recent publication by Bonthuis et al. shows a high prevalence of overweight or obesity in children with end-stage renal disease, particularly in renal transplant recipients. Underweight is more prevalent in infants than in other age groups. This study highlights the need to evaluate and implement interventional strategies in this patient population.

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References

  1. Ringback Weitoft, G., Eliasson, M. & Rosen, M. Underweight, overweight and obesity as risk factors for mortality and hospitalization. Scand. J. Public Health 36, 169–176 (2008).

    Article  Google Scholar 

  2. Juonala, M. et al. Childhood adiposity, adult adiposity, and cardiovascular risk factors. N. Engl. J. Med. 365, 1876–1885 (2011).

    Article  CAS  Google Scholar 

  3. Seidell, J. C., Verschuren, W. M., van Leer, E. M. & Kromhout, D. Overweight, underweight, and mortality. A prospective study of 48,287 men and women. Arch. Intern. Med. 156, 958–963 (1996).

    Article  CAS  Google Scholar 

  4. Black, R. E. et al. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 371, 243–260 (2008).

    Article  Google Scholar 

  5. Bonthuis, M. et al. Underweight, overweight and obesity in paediatric dialysis and renal transplant patients. Nephrol. Dial. Transplant. http://dx.doi.org/10.1093/ndt/gft259.

  6. Kambham, N., Markowitz, G. S., Valeri, A. M., Lin, J. & D'Agati, V. D. Obesity-related glomerulopathy: an emerging epidemic. Kidney Int. 59, 1498–1509 (2001).

    Article  CAS  Google Scholar 

  7. Hoogeveen, E. K. et al. Effect of obesity on the outcome of kidney transplantation: a 20-year follow-up. Transplantation 91, 869–874 (2011).

    Article  Google Scholar 

  8. Leavey, S. F. et al. Body mass index and mortality in 'healthier' as compared with 'sicker' haemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol. Dial. Transplant. 16, 2386–2394 (2001).

    Article  CAS  Google Scholar 

  9. Hoogeveen, E. K. et al. Obesity and mortality risk among younger dialysis patients. Clin. J. Am. Soc. Nephrol. 7, 280–288 (2012).

    Article  Google Scholar 

  10. Carrero, J. J. et al. Etiology of the protein-energy wasting syndrome in chronic kidney disease: a consensus statement from the International Society of Renal Nutrition and Metabolism (ISRNM). J. Ren. Nutr. 23, 77–90 (2013).

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Clinical Science, Division of Pediatrics, Intervention and Technology, Karolinska Institute, B 57 Huddinge, Karolinska University Hospital, Stockholm, SE-141 86, Sweden

    Rafael T. Krmar

  2. Department of Clinical Science, Division of Renal Medicine, Intervention and Technology, Karolinska Institute, K 56 Huddinge, Karolinska University Hospital, Stockholm, SE-141 86, Sweden

    Peter Bárány

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  1. Rafael T. Krmar
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  2. Peter Bárány
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Correspondence to Peter Bárány.

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The authors declare no competing financial interests.

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Krmar, R., Bárány, P. Obesity in children with end-stage renal disease. Nat Rev Nephrol 9, 707–708 (2013). https://doi.org/10.1038/nrneph.2013.223

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