Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Rheumatoid arthritis

Sedentary behaviour in RA — a new research agenda

Sedentary behaviour is reported to have adverse consequences for metabolic, functional and cardiovascular health — outcomes already prevalent in patients with rheumatoid arthritis (RA). This commentary considers the relevance of sedentary behaviour in the context of RA, highlighting the limitations of past work and offering suggestions for a new research agenda.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Proposed cyclic relationship between sedentary behaviour, inflammation and worsening disease outcomes in rheumatoid arthritis (RA).

References

  1. Sedentary Behavior Research Network. Letter to the editor: standardised use of the terms 'sedentary' and 'sedentary behaviours'. Appl. Physiol. Nutr. Metab. 37, 540–542 (2012).

  2. Biswas, A. et al. Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis. Ann. Intern. Med. 162, 123–132 (2015).

    Article  Google Scholar 

  3. Hamilton, M. T., Hamilton, D. G. & Zderic, T. Role of low energy expenditure and sitting in obesity, metabolic syndrome and type 2 diabetes and cardiovascular disease. Diabetes 56, 2655–2667 (2007).

    Article  CAS  Google Scholar 

  4. Yu, C. A. et al. Subjective and objective levels of physical activity and their association with cardiorespiratory fitness in rheumatoid arthritis patients. Arthritis Res. Ther. 17, 59 (2015).

    Article  Google Scholar 

  5. Prioreschi, A., Makda, M. A., Tikly, M. & McVeigh, J. A. Habitual physical activity, sedentary behaviour and bone health in rheumatoid arthritis. Int. J. Sports Med. 36, 1021–1026 (2015).

    Article  CAS  Google Scholar 

  6. Gilbert, A. L. et al. Comparison of subjective and objective measures of sedentary behavior using the Yale physical activity survey and accelerometry in patients with rheumatoid arthritis. J. Phys. Act. Health 13, 371–376 (2016).

    Article  Google Scholar 

  7. Metsios, G. S. et al. New resting energy expenditure prediction equations for patients with rheumatoid arthritis. Rheumatology 47, 500–506 (2008).

    Article  CAS  Google Scholar 

  8. Ainsworth, B. E. et al. Compendium of physical activities: classification of energy costs of human physical activities. Med. Sci. Sports Exerc. 25, 71–80 (1993).

    Article  CAS  Google Scholar 

  9. Tremblay, M. S., Colley, R. C., Saunders, T. J., Healy, G. N. & Owen, N. Physiological and health implications of a sedentary lifestyle. Appl. Physiol. Nutr. Metab. 35, 725–740 (2010).

    Article  Google Scholar 

  10. de Rezende, L.F., Rey-López, J. P., Matsudo, V. K. R. & do Carmo Luiz, O. Sedentary behavior and health outcomes among older adults: a systematic review. BMC Public Health 14, 33 (2014).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sally A. M. Fenton.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

PowerPoint slides

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fenton, S., Kitas, G. Sedentary behaviour in RA — a new research agenda. Nat Rev Rheumatol 12, 698–700 (2016). https://doi.org/10.1038/nrrheum.2016.179

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrrheum.2016.179

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing