Abstract
Many surgical options exist for women with stress urinary incontinence (SUI). The traditional gold standards of Burch retropubic colposuspension and pubovaginal slings are still appropriate treatment options for some patients, but randomized controlled trials have demonstrated that synthetic midurethral slings are just as effective as these traditional procedures but with less associated morbidity. Thus, midurethral slings—inserted via a retropubic or transobturator approach—have become the new gold standard first-line surgical treatment for women with uncomplicated SUI. Retropubic midurethral slings are associated with slightly higher success rates than transobturator slings, but at the cost of more postoperative complications. Pubovaginal slings remain an effective option for women with SUI who have failed other procedures, have had mesh complications, or who require concomitant urethral surgery. Single-incision slings have a number of benefits, including decreased operative times and early return to regular activities, but they are yet to be shown to be as effective as midurethral slings. Both retropubic and transobturator midurethral slings are effective for patients with mixed urinary incontinence, but the overall cure rate is lower than for patients with pure SUI. Based on the literature, a new gold standard first-line surgical treatment for women with SUI is the synthetic midurethral sling inserted through a retropubic or transobturator approach.
Key Points
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Many different surgical options have evolved for stress urinary incontinence (SUI), owing to its high prevalence; Burch colposuspension and autologous fascial pubovaginal slings are the traditional gold standards
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Randomized controlled trials have demonstrated that synthetic midurethral slings are as effective as traditional surgeries (such as Burch colposuspension and pubovaginal slings) but with less associated morbidity
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Midurethral slings have become the gold standard for treating uncomplicated female SUI
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Retropubic midurethral slings are associated with slightly higher success rates than transobturator slings, but at the cost of more postoperative complications
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Pubovaginal slings remain an effective option for women with SUI who have failed other procedures, have had mesh complications, or who require concomitant urethral surgery
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Single-incision slings are not as effective as traditional midurethral slings
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Change history
26 March 2013
In the version of this article initially published online [text explaining the error]. The error has been corrected for the print, HTML and PDF versions of the article.
References
Milsom, I. et al. Epidemiology of urinary and faecal incontinence and pelvic organ prolapse in Incontinence, 4th International Consultation (eds Abrams, P., Cardozo, L., Khoury, S. & Wein, A. J.) 35–112 (Health Publication Ltd, Paris, 2009).
Abrams, P. et al. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol. Urodyn. 21, 167–178 (2002).
Coyne, K. S., Zhou, Z., Thompson, C. & Versi, E. The impact on health-related quality of life of stress, urge and mixed urinary incontinence. BJU Int. 92, 731–735 (2003).
Ogah, J., Cody, J. D. & Rogerson, L. Minimally invasive synthetic suburethral sling operations for stress urinary incontinence in women. Cochrane Database Syst. Rev. CD006375 (2009).
Wu, J. M. et al. Predicting the number of women who will undergo incontinence and prolapse surgery, 2010 to 2050. Am. J. Obstet. Gynecol. 205, 230.e231–230.e235 (2011).
Hilton, P. Long-term follow-up studies in pelvic floor dysfunction: the Holy Grail or a realistic aim? BJOG 115, 135–143 (2008).
Leach, G. E. et al. Female Stress Urinary Incontinence Clinical Guidelines Panel summary report on surgical management of female stress urinary incontinence. The American Urological Association. J. Urol. 158, 875–880 (1997).
Ulmsten, U., Henriksson, L., Johnson, P. & Varhos, G. An ambulatory surgical procedure under local anesthesia for treatment of female urinary incontinence. Int. Urogynecol. J. Pelvic Floor Dysfunct. 7, 81–85 (1996).
Lapitan, M. C., Cody, D. J. & Grant, A. M. Open retropubic colposuspension for urinary incontinence in women. Cochrane Database Syst. Rev. CD002912 (2005).
Lapitan, M. C. & Cody, J. D. Open retropubic colposuspension for urinary incontinence in women. Cochrane Database Syst. Rev. 6, CD002912 (2012).
Glazener, C. M. & Cooper, K. Anterior vaginal repair for urinary incontinence in women. Cochrane Database Syst. Rev. CD001755 (2001).
Glazener, C. M. & Cooper, K. Bladder neck needle suspension for urinary incontinence in women. Cochrane Database Syst. Rev. CD003636 (2004).
Sivaslioglu, A. A., Unlubilgin, E., Keskin, H. L., Gelisen, O. & Dolen, I. The management of recurrent cases after the Burch colposuspension: 7 years experience. Arch. Gynecol. Obstet. 283, 787–790 (2011).
Kjolhede, P. Long-term efficacy of Burch colposuspension: a 14-year follow-up study. Acta Obstet. Gynecol. Scand. 84, 767–772 (2005).
Smith, A. R. et al. Surgery for urinary incontinence in women in Incontinence—4th International Consultation (eds Abrams, P., Cardozo, L., Khoury, S. & Wein, A.) 1191–1272 (Health Publication Ltd, Paris, 2009).
Aldridge, A. H. Transplantation of fascia for relief of stress incontinence. Am. J. Obstet. Gynecol. 44, 398–411 (1942).
Albo, M. E. et al. Burch colposuspension versus fascial sling to reduce urinary stress incontinence. N. Engl. J. Med. 356, 2143–2155 (2007).
Brubaker, L. et al. 5-Year continence rates, satisfaction and adverse events of Burch urethropexy and fascial sling surgery for urinary incontinence. J. Urol. 187, 1324–1330 (2012).
Welk, B. K. & Herschorn, S. The autologous fascia pubovaginal sling for complicated female stress incontinence. Can. Urol. Assoc. J. 6, 36–40 (2012).
Dmochowski, R. R., Padmanabhan, P. & Scarpero, H. M. Slings: autologous, biologic, synthetic, and midurethral in Campbell-Walsh Urology, Vol. 3 (eds Wein, A., Kavoussi, L. R., Novick, A. C., Partin, A. W. & Peters, C. A.) 2115–2167 (Elsevier Saunders, Philadelphia, 2012).
Ulmsten, U. & Petros, P. Intravaginal slingplasty (IVS): an ambulatory surgical procedure for treatment of female urinary incontinence. Scand. J. Urol. Nephrol. 29, 75–82 (1995).
Fong, E. D. & Nitti, V. W. Review article: mid-urethral synthetic slings for female stress urinary incontinence. BJU Int. 106, 596–608 (2010).
Delorme, E. Transobturator urethral suspension: mini-invasive procedure in the treatment of stress urinary incontinence in women [French]. Prog. Urol. 11, 1306–1313 (2001).
DeLancey, J. O. Structural support of the urethra as it relates to stress urinary incontinence: the hammock hypothesis. Am. J. Obstet. Gynecol. 170, 1713–1720 (1994).
Delorme, E., Droupy, S., de Tayrac, R. & Delmas, V. Transobturator tape (Uratape): a new minimally-invasive procedure to treat female urinary incontinence. Eur. Urol. 45, 203–207 (2004).
Rehman, H., Bezerra, C. C., Bruschini, H. & Cody, J. D. Traditional suburethral sling operations for urinary incontinence in women. Cochrane Database Syst. Rev. CD001754 (2011).
Novara, G. et al. Updated systematic review and meta-analysis of the comparative data on colposuspensions, pubovaginal slings, and midurethral tapes in the surgical treatment of female stress urinary incontinence. Eur. Urol. 58, 218–238 (2010).
Novara, G. et al. Tension-free midurethral slings in the treatment of female stress urinary incontinence: a systematic review and meta-analysis of randomized controlled trials of effectiveness. Eur. Urol. 52, 663–678 (2007).
Ward, K. L. & Hilton, P. Tension-free vaginal tape versus colposuspension for primary urodynamic stress incontinence: 5-year follow up. BJOG 115, 226–233 (2008).
Ward, K. & Hilton, P. Prospective multicentre randomised trial of tension-free vaginal tape and colposuspension as primary treatment for stress incontinence. BMJ 325, 67 (2002).
Jelovsek, J. E., Barber, M. D., Karram, M. M., Walters, M. D. & Paraiso, M. F. Randomised trial of laparoscopic Burch colposuspension versus tension-free vaginal tape: long-term follow up. BJOG 115, 219–225 (2008).
Dean, N., Herbison, P., Ellis, G. & Wilson, D. Laparoscopic colposuspension and tension-free vaginal tape: a systematic review. BJOG 113, 1345–1353 (2006).
Nilsson, C. G., Falconer, C. & Rezapour, M. Seven-year follow-up of the tension-free vaginal tape procedure for treatment of urinary incontinence. Obstet. Gynecol. 104, 1259–1262 (2004).
Nilsson, C. G., Palva, K., Rezapour, M. & Falconer, C. Eleven years prospective follow-up of the tension-free vaginal tape procedure for treatment of stress urinary incontinence. Int. Urogynecol. J. Pelvic Floor Dysfunct. 19, 1043–1047 (2008).
Spinosa, J. P. & Dubuis, P. Y. Suburethral sling inserted by the transobturator route in the treatment of female stress urinary incontinence: preliminary results in 117 cases. Eur. J. Obstet. Gynecol. Reprod. Biol. 123, 212–217 (2005).
Deval, B. et al. Objective and subjective cure rates after trans-obturator tape (OBTAPE) treatment of female urinary incontinence. Eur. Urol. 49, 373–377 (2006).
Yamada, B. S., Govier, F. E., Stefanovic, K. B. & Kobashi, K. C. High rate of vaginal erosions associated with the mentor ObTape. J. Urol. 176, 651–654 (2006).
Waltregny, D. et al. Inside out transobturator vaginal tape for the treatment of female stress urinary incontinence: interim results of a prospective study after a 1-year minimum followup. J. Urol. 175, 2191–2195 (2006).
Waltregny, D. & de Leval, J. The TVT-obturator surgical procedure for the treatment of female stress urinary incontinence: a clinical update. Int. Urogynecol. J. Pelvic Floor Dysfunct. 20, 337–348 (2009).
Latthe, P. M., Singh, P., Foon, R. & Toozs-Hobson, P. Two routes of transobturator tape procedures in stress urinary incontinence: a meta-analysis with direct and indirect comparison of randomized trials. BJU Int. 106, 68–76 (2010).
Sung, V. W., Schleinitz, M. D., Rardin, C. R., Ward, R. M. & Myers, D. L. Comparison of retropubic vs transobturator approach to midurethral slings: a systematic review and meta-analysis. Am. J. Obstet. Gynecol. 197, 3–11 (2007).
Richter, H. E. et al. Retropubic versus transobturator midurethral slings for stress incontinence. N. Engl. J. Med. 362, 2066–2076 (2010).
Morton, H. C. & Hilton, P. Urethral injury associated with minimally invasive mid-urethral sling procedures for the treatment of stress urinary incontinence: a case series and systematic literature search. BJOG 116, 1120–1126 (2009).
Daneshgari, F., Kong, W. & Swartz, M. Complications of mid urethral slings: important outcomes for future clinical trials. J. Urol. 180, 1890–1897 (2008).
Wijffels, S. A., Elzevier, H. W. & Lycklama a Nijeholt, A. A. Transurethral mesh resection after urethral erosion of tension-free vaginal tape: report of three cases and review of literature. Int. Urogynecol. J. Pelvic Floor Dysfunct. 20, 261–263 (2009).
Nguyen, J. N. Tape mobilization for urinary retention after tension-free vaginal tape procedures. Urology 66, 523–526 (2005).
Price, N., Slack, A., Khong, S. Y., Currie, I. & Jackson, S. The benefit of early mobilisation of tension-free vaginal tape in the treatment of post-operative voiding dysfunction. Int. Urogynecol. J. Pelvic Floor Dysfunct. 20, 855–858 (2009).
Leng, W. W., Davies, B. J., Tarin, T., Sweeney, D. D. & Chancellor, M. B. Delayed treatment of bladder outlet obstruction after sling surgery: association with irreversible bladder dysfunction. J. Urol. 172, 1379–1381 (2004).
Kobashi, K. C. & Govier, F. E. Management of vaginal erosion of polypropylene mesh slings. J. Urol. 169, 2242–2243 (2003).
Laurikainen, E. et al. Retropubic compared with transobturator tape placement in treatment of urinary incontinence: a randomized controlled trial. Obstet. Gynecol. 109, 4–11 (2007).
Wang, W., Zhu, L. & Lang, J. Transobturator tape procedure versus tension-free vaginal tape for treatment of stress urinary incontinence. Int. J. Gynaecol. Obstet. 104, 113–116 (2009).
Long, C. Y. et al. Comparison of tension-free vaginal tape and transobturator tape procedure for the treatment of stress urinary incontinence. Curr. Opin. Obstet. Gynecol. 21, 342–347 (2009).
Duckett, J. R. & Jain, S. Groin pain after a tension-free vaginal tape or similar suburethral sling: management strategies. BJU Int. 95, 95–97 (2005).
de Leval, J. Novel surgical technique for the treatment of female stress urinary incontinence: transobturator vaginal tape inside-out. Eur. Urol. 44, 724–730 (2003).
Krauth, J. S. et al. Sub-urethral tape treatment of female urinary incontinence—morbidity assessment of the trans-obturator route and a new tape (I-STOP): a multi-centre experiment involving 604 cases. Eur. Urol. 47, 102–106 (2005).
Roth, T. M. Management of persistent groin pain after transobturator slings. Int. Urogynecol. J. Pelvic Floor Dysfunct. 18, 1371–1373 (2007).
Mahajan, S. T., Kenton, K., Bova, D. A. & Brubaker, L. Transobturator tape erosion associated with leg pain. Int. Urogynecol. J. Pelvic Floor Dysfunct. 17, 66–68 (2006).
Wolter, C. E., Starkman, J. S., Scarpero, H. M. & Dmochowski, R. R. Removal of transobturator midurethral sling for refractory thigh pain. Urology 72, e461–e463 (2008).
Tartaglia, E. et al. Third-generation tension-free tape for female stress urinary incontinence. J. Urol. 182, 612–615 (2009).
Cornu, J. N. et al. Midterm prospective evaluation of TVT-Secur reveals high failure rate. Eur. Urol. 58, 157–161 (2010).
Gauruder-Burmester, A. & Popken, G. The MiniArc sling system in the treatment of female stress urinary incontinence. Int. Braz. J. Urol. 35, 334–341 (2009).
Pickens, R. B., Klein, F. A., Mobley, J. D. 3rd & White, W. M. Single incision mid-urethral sling for treatment of female stress urinary incontinence. Urology 77, 321–324 (2011).
Kennelly, M. J., Moore, R., Nguyen, J. N., Lukban, J. C. & Siegel, S. Prospective evaluation of a single incision sling for stress urinary incontinence. J. Urol. 184, 604–609 (2010).
Tincello, D. G. et al. The TVT worldwide observational registry for long-term data: safety and efficacy of suburethral sling insertion approaches for stress urinary incontinence in women. J. Urol. 186, 2310–2315 (2011).
Hinoul, P. et al. A randomized, controlled trial comparing an innovative single incision sling with an established transobturator sling to treat female stress urinary incontinence. J. Urol. 185, 1356–1362 (2011).
Abdel-Fattah, M., Ford, J. A., Lim, C. P. & Madhuvrata, P. Single-incision mini-slings versus standard midurethral slings in surgical management of female stress urinary incontinence: a meta-analysis of effectiveness and complications. Eur. Urol. 60, 468–480 (2011).
Meschia, M. et al. Short-term outcomes with the Ajust™ system: a new single incision sling for the treatment of stress urinary incontinence. Int. Urogynecol. J. Pelvic Floor Dysfunct. 22, 177–182 (2011).
US FDA. Urogynecologic surgical mesh implants [online], (2012).
Hunskaar, S. et al. Epidemiology and natural history of urinary incontinence in women. Urology 62, 16–23 (2003).
Nilsson, C. G. & Kuuva, N. The tension-free vaginal tape procedure is successful in the majority of women with indications for surgical treatment of urinary stress incontinence. BJOG 108, 414–419 (2001).
Lee, J. H., Cho, M. C., Oh, S. J., Kim, S. W. & Paick, J. S. Long-term outcome of the tension-free vaginal tape procedure in female urinary incontinence: a 6-year follow-up. Korean J. Urol. 51, 409–415 (2010).
Houwert, R. M. et al. Risk factors for failure of retropubic and transobturator midurethral slings. Am. J. Obstet. Gynecol. 201, e201–e208 (2009).
Paick, J. S., Cho, M. C., Oh, S. J., Kim, S. W. & Ku, J. H. Factors influencing the outcome of mid urethral sling procedures for female urinary incontinence. J. Urol. 178, 985–989 (2007).
Holmgren, C., Nilsson, S., Lanner, L. & Hellberg, D. Long-term results with tension-free vaginal tape on mixed and stress urinary incontinence. Obstet. Gynecol. 106, 38–43 (2005).
Jain, P., Jirschele, K., Botros, S. M. & Latthe, P. M. Effectiveness of midurethral slings in mixed urinary incontinence: a systematic review and meta-analysis. Int. Urogynecol. J. 22, 923–932 (2011).
Dmochowski, R. R. et al. Update of AUA guideline on the surgical management of female stress urinary incontinence. J. Urol. 183, 1906–1914 (2010).
Chapple, C. & Milsom, I. Urinary incontinence and pelvic prolapse: epidemiology and pathophysiology in Campbell-Walsh Urology Vol. 3 (eds Wein, A., Kavoussi, L. R., Novick, A. C., Partin, A. W. & Peters, C. A.) 1871–1895 (Elsevier Saunders, Philadelphia, 2012).
Kuo, H. C. Videourodynamic analysis of the relationship of Valsalva and cough leak point pressures in women with stress urinary incontinence. Urology 61, 544–548 (2003).
Fleischmann, N., Flisser, A. J., Blaivas, J. G. & Panagopoulos, G. Sphincteric urinary incontinence: relationship of vesical leak point pressure, urethral mobility and severity of incontinence. J. Urol. 169, 999–1002 (2003).
Kayigil, O., Iftekhar Ahmed, S. & Metin, A. The coexistence of intrinsic sphincter deficiency with type II stress incontinence. J. Urol. 162, 1365–1366 (1999).
Koelbl, H. et al. Pathophysiology of urinary incontinence, faecal incontinence, and pelvic organ prolapse in Incontinence—4th International Consultation (eds Abrams, P., Cardozo, L., Khoury, S. & Wein, A.) 255–330 (Health Publications Ltd, Paris, 2009).
Paick, J. S. et al. Tension-free vaginal tape procedure for the treatment of mixed urinary incontinence: significance of maximal urethral closure pressure. J. Urol. 172, 1001–1005 (2004).
Nager, C. W. et al. Baseline urodynamic predictors of treatment failure 1 year after mid urethral sling surgery. J. Urol. 186, 597–603 (2011).
Rodriguez, L. V., de Almeida, F., Dorey, F. & Raz, S. Does Valsalva leak point pressure predict outcome after the distal urethral polypropylene sling? Role of urodynamics in the sling era. J. Urol. 172, 210–214 (2004).
Song, P. H. et al. The 7-year outcome of the tension-free vaginal tape procedure for treating female stress urinary incontinence. BJU Int. 104, 1113–1117 (2009).
Fritel, X., Zabak, K., Pigne, A., Demaria, F. & Benifla, J. L. Predictive value of urethral mobility before suburethral tape procedure for urinary stress incontinence in women. J. Urol. 168, 2472–2475 (2002).
Rezapour, M., Falconer, C. & Ulmsten, U. Tension-free vaginal tape (TVT) in stress incontinent women with intrinsic sphincter deficiency (ISD)—a long-term follow-up. Int. Urogynecol. J. Pelvic Floor Dysfunct. 12 (Suppl. 2), S12–S14 (2001).
Ghezzi, F. et al. Tension-free vaginal tape for the treatment of urodynamic stress incontinence with intrinsic sphincteric deficiency. Int. Urogynecol. J. Pelvic Floor Dysfunct. 17, 335–339 (2006).
Haliloglu, B., Karateke, A., Coksuer, H., Peker, H. & Cam, C. The role of urethral hypermobility and intrinsic sphincteric deficiency on the outcome of transobturator tape procedure: a prospective study with 2-year follow-up. Int. Urogynecol. J. 21, 173–178 (2010).
Jeon, M. J., Jung, H. J., Chung, S. M., Kim, S. K. & Bai, S. W. Comparison of the treatment outcome of pubovaginal sling, tension-free vaginal tape, and transobturator tape for stress urinary incontinence with intrinsic sphincter deficiency. Am. J. Obstet. Gynecol. 199, 76.e1–76.e4 (2008).
Rechberger, T., Futyma, K., Jankiewicz, K., Adamiak, A. & Skorupski, P. The clinical effectiveness of retropubic (IVS-02) and transobturator (IVS-04) midurethral slings: randomized trial. Eur. Urol. 56, 24–30 (2009).
Schierlitz, L. et al. Effectiveness of tension-free vaginal tape compared with transobturator tape in women with stress urinary incontinence and intrinsic sphincter deficiency: a randomized controlled trial. Obstet. Gynecol. 112, 1253–1261 (2008).
Pradhan, A., Jain, P. & Latthe, P. M. Effectiveness of midurethral slings in recurrent stress urinary incontinence: a systematic review and meta-analysis. Int. Urogynecol. J. 23, 831–841 (2012).
But, I. & Faganelj, M. Complications and short-term results of two different transobturator techniques for surgical treatment of women with urinary incontinence: a randomized study. Int. Urogynecol. J. Pelvic Floor Dysfunct. 19, 857–861 (2008).
Barber, M. D. et al. Transobturator tape compared with tension-free vaginal tape for the treatment of stress urinary incontinence: a randomized controlled trial. Obstet. Gynecol. 111, 611–621 (2008).
Rinne, K. et al. A randomized trial comparing TVT with TVT-O: 12-month results. Int. Urogynecol. J. Pelvic Floor Dysfunct. 19, 1049–1054 (2008).
Porena, M. et al. Tension-free vaginal tape versus transobturator tape as surgery for stress urinary incontinence: results of a multicentre randomised trial. Eur. Urol. 52, 1481–1490 (2007).
Meschia, M. et al. Peri-operative morbidity and early results of a randomised trial comparing TVT and TVT-O. Int. Urogynecol. J. Pelvic Floor Dysfunct. 18, 1257–1261 (2007).
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A. Cox, S. Herschorn and L. Lee contributed to the researching of data for the article, discussion of content and writing the manuscript. A. Cox and S. Herschorn reviewed/edited the manuscript before submission.
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S. Herschorn declares that he has been a Consultant for American Medical Systems and Promedon, and has received grant/research support (inc. clinical trials) from Contura (Johnson & Johnson). The other authors declare no competing interests.
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Cox, A., Herschorn, S. & Lee, L. Surgical management of female SUI: is there a gold standard?. Nat Rev Urol 10, 78–89 (2013). https://doi.org/10.1038/nrurol.2012.243
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DOI: https://doi.org/10.1038/nrurol.2012.243
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