The ideal first-line treatment of cisplatin-ineligible patients with metastatic urothelial carcinoma (mUC) remains unknown pending results of randomized trials. Although mUC tumours are sensitive to chemotherapy, response durations are short. A new retrospective study provides data on the effectiveness of first-line PD-1/PD-L1 inhibitors compared with carboplatin-based chemotherapy in this setting.
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Apolo, A.B. Determining superior first-line therapy in metastatic bladder cancer. Nat Rev Urol 16, 698–699 (2019). https://doi.org/10.1038/s41585-019-0245-8
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DOI: https://doi.org/10.1038/s41585-019-0245-8
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